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• W171314903 abstract "Fever of unknown origin (FUO) is a diagnostic challenge for the wide range of possible causes involved. The aim of our work was to evaluate the role of [18F]-fluorodeoxyglucose positron emission tomography computed tomography ([18F]-FDG-PET/CT) in managing patients with classical FUO. Twenty-four consecutive patients (16 women, eight men; mean age, 56.5 years) with a diagnosis of FUO based on routine investigations were retrospectively studied. All underwent [18F]-FDG-PET/CT, which was considered true positive when the result was in agreement with the final diagnosis. A final diagnosis was reached in 17 of 24 patients (vasculitis, n=5; autoimmune disorder, n=2; neoplasm, n=3; infectious disease, n=6; biliary microlithiasis, n=1). In the remaining seven cases, no final diagnosis was established. PET-CT was useful in identifying aetiology in 11 patients, showing a diagnostic yield of 46% (11/24). Among the 11 cases with a negative PET scan, 10 did not show a worsening of the clinical condition. This study underlines the crucial role of [18F]-FDG-PET/CT in managing patients with FUO. If prospective trials on this topic confirm the present findings, PET/CT should be incorporated in the routine diagnostic work-up of patients with classical FUO." @default.
• W171314903 created "2016-06-24" @default.
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• W171314903 date "2011-03-07" @default.
• W171314903 modified "2023-10-12" @default.
• W171314903 title "Role of integrated PET/CT with [18F]-FDG in the management of patients with fever of unknown origin: a single-centre experience" @default.
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• W171314903 doi "https://doi.org/10.1007/s11547-011-0649-x" @default.
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