Matches in SemOpenAlex for { <https://semopenalex.org/work/W1717769564> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W1717769564 abstract "Manduca sexta larvae (tobacco hornworm) early in their fifth and final larval stage have been reported to have more robust immune responses to Photorabdus luminscens compared to animals later in that stage. We hypothesized that the robust immune response in early stage caterpillars would result in varying hemolymph bacterial loads and survival to other bacterial infections. Early stage M. sexta injected with non-pathogenic E. coli had 25-fold higher bacterial loads in hemolymph than those injected later. In addition, early stage M. sexta injected with pathogenic Stenotrophomonas maltohphilia died twice as fast as those injected later. These data demonstrate an ineffective immune response in early stage caterpillars. We also hypothesized that the robust immune response in early stage caterpillars would affect other aspects of physiology, such as development and growth. Early stage M. sexta injected with E. coli or S. maltophilia exhibited developmental and growth rates twice as slow as those injected later. Sickness-induced anorexia occurs in many taxa and may be the cause of the growth rate and developmental delays in infected caterpillars. While it is clear that development affects immunity, it is unclear why the age-immunity relationship varies with different bacteria. Because of the importance of insects as pests and pollinators, understanding how immunity varies throughout development is critical." @default.
- W1717769564 created "2016-06-24" @default.
- W1717769564 creator A5025023534 @default.
- W1717769564 creator A5049736662 @default.
- W1717769564 creator A5071746915 @default.
- W1717769564 creator A5084116853 @default.
- W1717769564 date "2014-04-01" @default.
- W1717769564 modified "2023-09-27" @default.
- W1717769564 title "Aging increases resistance to bacterial infection in the tobacco hornworm, Manduca sexta (1100.4)" @default.
- W1717769564 doi "https://doi.org/10.1096/fasebj.28.1_supplement.1100.4" @default.
- W1717769564 hasPublicationYear "2014" @default.
- W1717769564 type Work @default.
- W1717769564 sameAs 1717769564 @default.
- W1717769564 citedByCount "0" @default.
- W1717769564 crossrefType "journal-article" @default.
- W1717769564 hasAuthorship W1717769564A5025023534 @default.
- W1717769564 hasAuthorship W1717769564A5049736662 @default.
- W1717769564 hasAuthorship W1717769564A5071746915 @default.
- W1717769564 hasAuthorship W1717769564A5084116853 @default.
- W1717769564 hasConcept C100068826 @default.
- W1717769564 hasConcept C173758957 @default.
- W1717769564 hasConcept C203014093 @default.
- W1717769564 hasConcept C2776071262 @default.
- W1717769564 hasConcept C2778883795 @default.
- W1717769564 hasConcept C2779082490 @default.
- W1717769564 hasConcept C2779341262 @default.
- W1717769564 hasConcept C2780312687 @default.
- W1717769564 hasConcept C523546767 @default.
- W1717769564 hasConcept C54355233 @default.
- W1717769564 hasConcept C59822182 @default.
- W1717769564 hasConcept C86803240 @default.
- W1717769564 hasConcept C8891405 @default.
- W1717769564 hasConcept C89423630 @default.
- W1717769564 hasConcept C90856448 @default.
- W1717769564 hasConceptScore W1717769564C100068826 @default.
- W1717769564 hasConceptScore W1717769564C173758957 @default.
- W1717769564 hasConceptScore W1717769564C203014093 @default.
- W1717769564 hasConceptScore W1717769564C2776071262 @default.
- W1717769564 hasConceptScore W1717769564C2778883795 @default.
- W1717769564 hasConceptScore W1717769564C2779082490 @default.
- W1717769564 hasConceptScore W1717769564C2779341262 @default.
- W1717769564 hasConceptScore W1717769564C2780312687 @default.
- W1717769564 hasConceptScore W1717769564C523546767 @default.
- W1717769564 hasConceptScore W1717769564C54355233 @default.
- W1717769564 hasConceptScore W1717769564C59822182 @default.
- W1717769564 hasConceptScore W1717769564C86803240 @default.
- W1717769564 hasConceptScore W1717769564C8891405 @default.
- W1717769564 hasConceptScore W1717769564C89423630 @default.
- W1717769564 hasConceptScore W1717769564C90856448 @default.
- W1717769564 hasIssue "S1" @default.
- W1717769564 hasLocation W17177695641 @default.
- W1717769564 hasOpenAccess W1717769564 @default.
- W1717769564 hasPrimaryLocation W17177695641 @default.
- W1717769564 hasRelatedWork W1507507951 @default.
- W1717769564 hasRelatedWork W1594388332 @default.
- W1717769564 hasRelatedWork W1966006870 @default.
- W1717769564 hasRelatedWork W1985234691 @default.
- W1717769564 hasRelatedWork W2005404303 @default.
- W1717769564 hasRelatedWork W2030942569 @default.
- W1717769564 hasRelatedWork W2048672860 @default.
- W1717769564 hasRelatedWork W2069799960 @default.
- W1717769564 hasRelatedWork W2153027472 @default.
- W1717769564 hasRelatedWork W2769030298 @default.
- W1717769564 hasVolume "28" @default.
- W1717769564 isParatext "false" @default.
- W1717769564 isRetracted "false" @default.
- W1717769564 magId "1717769564" @default.
- W1717769564 workType "article" @default.