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- W171782888 endingPage "174" @default.
- W171782888 startingPage "141" @default.
- W171782888 abstract "Experiments initiated by W.C. Young and collaborators in the early 1930s (reviewed by Young 1961, 1969) have dominated the work on control of feminine mating behavior by ovarian hormones. The conceptual developments of this group still guide research in the field as well as in related fields, e.g., the hormonal control of body weight regulation (Wade 1976). In initial attempts to identify the endocrine factors controlling the induction of sexual receptivity in the guinea pig, it was found that growth of the Graafian follicle was accelerated in the hours preceding the onset of sexual behavior (Myers et al. 1936). Knowing that exogenous administration of luteinizing hormone (LH) induces rapid growth of the preovulatory follicle (Foster and Hisaw 1935), Dempsey et al. (1936) found that administration of LH to cyclic guinea pigs induced sexual receptivity if given at a stage of the estrous cycle when the ovaries contained ripe follicles; but not if given early in the cycle or if given to ovariectomized animals pretreated with estrogen. It was shown that the LH acted on the well-developed ovarian follicles, stimulating the production of a factor which in turn induced the behavior. The follicular factor was identified as progesterone. Thus, the hormonal factors controlling the display of sexual behavior during the guinea pig estrous cycle were shown to be estrogen and progesterone, and it was shown that progesterone acted on a background of estrogen priming, i.e., after a period of estrogen conditioning." @default.
- W171782888 created "2016-06-24" @default.
- W171782888 creator A5015315436 @default.
- W171782888 date "1985-01-01" @default.
- W171782888 modified "2023-10-17" @default.
- W171782888 title "Estradiol-Progesterone Interactions in the Reproductive Behavior of Female Rats" @default.
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