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- W1719180432 endingPage "180" @default.
- W1719180432 startingPage "145" @default.
- W1719180432 abstract "Resolution of multimeric forms of circular plasmids and chromosomes is mediated by site-specific recombination, an efficient and tightly controlled DNA breakage and joining reaction occurring at the level of determined DNA sequences. Site-specific recombinases, the enzymes that catalyze this type of reaction, fall into two families of proteins: the serine-recombinase and tyrosine-recombinase families. The chapter discusses the mechanisms that generate DNA multimers and their consequence on the segregational stability of bacterial replicons, and also provides an overview of the variety of site-specific resolution systems found on circular plasmids and chromosomes and their relationship to other recombination systems. It focuses on site-specific resolution systems of the serine-recombinase family, and plasmid and chromosome resolution systems of the tyrosine recombinase family. The topology of the recombination reaction catalyzed by other resolvases of the serine-recombinase family, such as the ParA protein of RP4/RK2, the resolvase of ISXc5, the Sin recombinase of Staphylococcus aureus, and the β recombinase of pSM19035, was found to be identical to that reported for the cointegrate resolution system of Tn3-family transposons. Studies on plasmid and transposon resolution systems provide fascinating examples of convergent evolution, in which structurally and biochemically unrelated molecular machines have been adapted to bring about functionally similar DNA rearrangements in an exquisitely controlled manner." @default.
- W1719180432 created "2016-06-24" @default.
- W1719180432 creator A5015700197 @default.
- W1719180432 creator A5018253322 @default.
- W1719180432 creator A5044268303 @default.
- W1719180432 date "2014-04-08" @default.
- W1719180432 modified "2023-10-10" @default.
- W1719180432 title "DNA Site-Specific Resolution Systems" @default.
- W1719180432 cites W1032034317 @default.
- W1719180432 cites W1204884779 @default.
- W1719180432 cites W1225265168 @default.
- W1719180432 cites W1487083347 @default.
- W1719180432 cites W1491021666 @default.
- W1719180432 cites W1504533209 @default.
- W1719180432 cites W1507245927 @default.
- W1719180432 cites W1510489127 @default.
- W1719180432 cites W1529246944 @default.
- W1719180432 cites W1532522639 @default.
- W1719180432 cites W1538570542 @default.
- W1719180432 cites W1538904365 @default.
- W1719180432 cites W1547287134 @default.
- W1719180432 cites W1547739886 @default.
- W1719180432 cites W1561410733 @default.
- W1719180432 cites W1565176526 @default.
- W1719180432 cites W1570361288 @default.
- W1719180432 cites W1579268353 @default.
- W1719180432 cites W1590546489 @default.
- W1719180432 cites W1598366419 @default.
- W1719180432 cites W1600612104 @default.
- W1719180432 cites W1608728627 @default.
- W1719180432 cites W1660492311 @default.
- W1719180432 cites W1703269095 @default.
- W1719180432 cites W1727852497 @default.
- W1719180432 cites W1752095998 @default.
- W1719180432 cites W1830178386 @default.
- W1719180432 cites W1840427270 @default.
- W1719180432 cites W1866948286 @default.
- W1719180432 cites W1945411900 @default.
- W1719180432 cites W1947248835 @default.
- W1719180432 cites W1953158171 @default.
- W1719180432 cites W1957797796 @default.
- W1719180432 cites W1964051028 @default.
- W1719180432 cites W1964097784 @default.
- W1719180432 cites W1966334685 @default.
- W1719180432 cites W1967071624 @default.
- W1719180432 cites W1968511538 @default.
- W1719180432 cites W1970210978 @default.
- W1719180432 cites W1970480018 @default.
- W1719180432 cites W1970494673 @default.
- W1719180432 cites W1970799821 @default.
- W1719180432 cites W1973717540 @default.
- W1719180432 cites W1973964227 @default.
- W1719180432 cites W1974878524 @default.
- W1719180432 cites W1976567461 @default.
- W1719180432 cites W1978900648 @default.
- W1719180432 cites W1980606854 @default.
- W1719180432 cites W1981501758 @default.
- W1719180432 cites W1982650033 @default.
- W1719180432 cites W1982863905 @default.
- W1719180432 cites W1983025199 @default.
- W1719180432 cites W1983228265 @default.
- W1719180432 cites W1983414988 @default.
- W1719180432 cites W1983993556 @default.
- W1719180432 cites W1984626450 @default.
- W1719180432 cites W1985085715 @default.
- W1719180432 cites W1986189576 @default.
- W1719180432 cites W1987170498 @default.
- W1719180432 cites W1987456338 @default.
- W1719180432 cites W1987587101 @default.
- W1719180432 cites W1988309865 @default.
- W1719180432 cites W1989700291 @default.
- W1719180432 cites W1989790258 @default.
- W1719180432 cites W1991511251 @default.
- W1719180432 cites W1995364560 @default.
- W1719180432 cites W1997130788 @default.
- W1719180432 cites W1999232678 @default.
- W1719180432 cites W1999346746 @default.
- W1719180432 cites W2000598224 @default.
- W1719180432 cites W2004325812 @default.
- W1719180432 cites W2005031387 @default.
- W1719180432 cites W2007255416 @default.
- W1719180432 cites W2009355359 @default.
- W1719180432 cites W2010653401 @default.
- W1719180432 cites W2010724194 @default.
- W1719180432 cites W2013538591 @default.
- W1719180432 cites W2014035248 @default.
- W1719180432 cites W2014773622 @default.
- W1719180432 cites W2017778575 @default.
- W1719180432 cites W2018679268 @default.
- W1719180432 cites W2019451098 @default.
- W1719180432 cites W2019635509 @default.
- W1719180432 cites W2020607945 @default.
- W1719180432 cites W2021159410 @default.
- W1719180432 cites W2022382148 @default.
- W1719180432 cites W2023054266 @default.
- W1719180432 cites W2023184158 @default.
- W1719180432 cites W2025453272 @default.
- W1719180432 cites W2025587028 @default.