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- W17200767 abstract "A primary indication for red blood cell (RBC) transfusion is to prevent the adverse effects of inadequate tissue oxygenation when hemoglobin (Hgb) is low and physiological mechanisms to compensate for diminished oxygen delivery are inadequate. Indications for transfusion have historically been guided by Hgb concentration. The conundrum facing researchers and healthcare providers is to identify the point when critical tissue oxygen delivery is impaired to the extent that transfusion is required in a patient while avoiding unnecessary transfusion. This article will review basic physiological responses to RBC loss and indications for RBC transfusion in patients with acute and chronic anemia and conclude with a discussion of alternatives to transfusion." @default.
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- W17200767 date "2014-01-01" @default.
- W17200767 modified "2023-10-14" @default.
- W17200767 title "The Therapeutic Use of Red Blood Cells" @default.
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- W17200767 doi "https://doi.org/10.1016/b978-0-12-386456-7.06205-5" @default.
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