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- W17211110 abstract "Studies of regional cerebral blood flow in organic dementia, mainly of the presenile/senile and the multi-infarct type are briefly reviewed. These patients show a reduction of the mean cerebral blood flow which is grossly proportional to the intellectual deficit. In addition, regional flow reductions correlate in a meaningful way to subsymptoms of the dementia, e.g., to memory deficits, speech difficulties, and symptoms of agnosia. Emphasis is given to the fact that even in the resting state, awake patients with organic dementia show a low flow (activity) in frontal and postcentral-temporal regions. The flow landscape is then of the hypofrontal, instead of the normal hyperfrontal type. In addition, the regions mentioned (the association areas) can not be activated in a normal fashion during psychological testing. The hypofrontal flow pattern and the inability to activate association areas appears to be of fundamental importance for the defects in higher functions which are so clearly evident in organic dementia." @default.
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- W17211110 date "1979-01-01" @default.
- W17211110 modified "2023-09-27" @default.
- W17211110 title "Activity Distribution in the Cerebral Cortex in Organic Dementia as Revealed by Measurements of Regional Cerebral Blood Flow" @default.
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- W17211110 doi "https://doi.org/10.1007/978-3-642-67304-7_18" @default.
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