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• W1723359935 abstract "Urinary tract infection (UTI) is one of the most common sources of infection in children under five. Prompt diagnosis and treatment is important to reduce the risk of renal scarring. Rapid, cost-effective, methods of UTI diagnosis are required as an alternative to culture.We conducted a systematic review to determine the diagnostic accuracy of rapid tests for detecting UTI in children under five years of age.The evidence supports the use of dipstick positive for both leukocyte esterase and nitrite (pooled LR+ = 28.2, 95% CI: 17.3, 46.0) or microscopy positive for both pyuria and bacteriuria (pooled LR+ = 37.0, 95% CI: 11.0, 125.9) to rule in UTI. Similarly dipstick negative for both LE and nitrite (Pooled LR- = 0.20, 95% CI: 0.16, 0.26) or microscopy negative for both pyuria and bacteriuria (Pooled LR- = 0.11, 95% CI: 0.05, 0.23) can be used to rule out UTI. A test for glucose showed promise in potty-trained children. However, all studies were over 30 years old. Further evaluation of this test may be useful.Dipstick negative for both LE and nitrite or microscopic analysis negative for both pyuria and bacteriuria of a clean voided urine, bag, or nappy/pad specimen may reasonably be used to rule out UTI. These patients can then reasonably be excluded from further investigation, without the need for confirmatory culture. Similarly, combinations of positive tests could be used to rule in UTI, and trigger further investigation." @default.
• W1723359935 created "2016-06-24" @default.
• W1723359935 creator A5016321309 @default.
• W1723359935 creator A5032281765 @default.
• W1723359935 creator A5065584931 @default.
• W1723359935 creator A5074205715 @default.
• W1723359935 creator A5077388783 @default.
• W1723359935 date "2005-04-05" @default.
• W1723359935 modified "2023-10-10" @default.
• W1723359935 title "Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review" @default.
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• W1723359935 doi "https://doi.org/10.1186/1471-2431-5-4" @default.
• W1723359935 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1084351" @default.
• W1723359935 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15811182" @default.
• W1723359935 hasPublicationYear "2005" @default.
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