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- W172761657 abstract "The binding of a small ligand such as O2 or CO to a heme protein is one of the simplest biological processes. Nevertheless even the reaction (1) $${text{Mb}},{text{ + }},{text{CO}}, leftrightarrow ,{text{MbCO,}}$$ the binding of CO to the “simple” storage protein myoglobin, is extremely complex. The complexity makes a quantitative description difficult but at the same time reactions of the type (1) become tools to explore protein properties. Goals of such studies are the phenomenological description of the reaction (1), the understanding of the reaction mechanisms involved in (1), the characterization and classification of the protein motions that accompany the ligand binding, and the connection between the protein structure and the parameters of reaction (1). None of these goals has been fully reached. Here I try to sketch some results and some problems and controversies." @default.
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- W172761657 date "1987-01-01" @default.
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- W172761657 title "Heme Protein Reactions: Models, Concepts, and Problems" @default.
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- W172761657 doi "https://doi.org/10.1007/978-3-642-71705-5_3" @default.
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