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- W1728268803 abstract "The brain's default mode network (DMN) has attracted tremendous attention, but its topology still lacks a substantial and operative definition. At the same time, recent efforts based on coactivation analysis suggest significant involvement of concomitant activation as an origin of synchronous activity, which is the basis of the network detection. Therefore, to establish the biological significance of the intrinsic remote connectivity, understanding such co-occurrence networks may be crucial. This study shows the results of monitoring the network's signal variation during random transitions among two divergent tasks and rest epochs. The subset of the DMN nodes showed three distinct activity levels; it was simultaneously characterized by the lack of a transition response between blocks. Additional connectivity analysis revealed components covering the other DMN nodes showing overshooting in response to a transition that were still connected to the posterior cingulate cortices (PCC), but by different signal components. The overall finding of multiple connectivity modes in the DMN provides a relevant explanation about the two seemingly contradictory characteristics of the network, robustness and variation." @default.
- W1728268803 created "2016-06-24" @default.
- W1728268803 creator A5069997869 @default.
- W1728268803 creator A5090155022 @default.
- W1728268803 date "2015-05-01" @default.
- W1728268803 modified "2023-10-14" @default.
- W1728268803 title "Functional Heterogeneity in the Default Mode Network Edges" @default.
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- W1728268803 doi "https://doi.org/10.1089/brain.2014.0256" @default.
- W1728268803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25409139" @default.
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