FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1729594682> ?p ?o ?g. }

• W1729594682 endingPage "109" @default.
• W1729594682 startingPage "97" @default.
• W1729594682 abstract "The Burkholderia cepacia complex comprises groups of genomovars (genotypically distinct strains with very similar phenotypes) that have emerged as important opportunistic pathogens in cystic fibrosis (CF) patients. The inflammatory response against bacteria in the airways of CF individuals is dominated by polymorphonuclear cells and involves the generation of oxidative stress, which leads to further inflammation and tissue damage. Bacterial catalase, catalase-peroxidase and superoxide dismutase activities may contribute to the survival of B. cepacia following exposure to reactive oxygen metabolites generated by host cells in response to infection. In the present study the authors investigated the production of catalase, peroxidase and SOD by isolates belonging to various genomovars of the B. cepacia complex. Production of both catalase and SOD was maximal during late stationary phase in almost all isolates examined. Native PAGE identified 13 catalase electrophoretotypes and two SOD electrophoretotypes (corresponding to an Fe-SOD class) in strains belonging to the six genomovars of the B. cepacia complex. Seven out of 11 strains displaying high-level survival after H2O2 treatment in vitro had a bifunctional catalase/peroxidase, and included all the genomovar III strains examined. These isolates represent most of the epidemic isolates that are often associated with the cepacia syndrome. The majority of the isolates from all the genomovars were resistant to extracellular (O_{2}^{{-}}) , while resistance to intracellularly generated (O_{2}^{{-}}) was highly variable and could not be correlated with the detected levels of SOD activity. Altogether the results suggest that resistance to toxic oxygen metabolites from extracellular sources may be a factor involved in the persistence of B. cepacia in the airways of CF individuals." @default.
• W1729594682 created "2016-06-24" @default.
• W1729594682 creator A5019344957 @default.
• W1729594682 creator A5041019879 @default.
• W1729594682 date "2001-01-01" @default.
• W1729594682 modified "2023-09-26" @default.
• W1729594682 title "In vitro resistance of Burkholderia cepacia complex isolates to reactive oxygen species in relation to catalase and superoxide dismutase production" @default.
• W1729594682 cites W1509038183 @default.
• W1729594682 cites W1538849969 @default.
• W1729594682 cites W1548442754 @default.
• W1729594682 cites W1574291747 @default.
• W1729594682 cites W1580575515 @default.
• W1729594682 cites W1733814841 @default.
• W1729594682 cites W1841321987 @default.
• W1729594682 cites W1891988303 @default.
• W1729594682 cites W1924464275 @default.
• W1729594682 cites W1939352827 @default.
• W1729594682 cites W1944603603 @default.
• W1729594682 cites W1950869481 @default.
• W1729594682 cites W1960661650 @default.
• W1729594682 cites W1967398861 @default.
• W1729594682 cites W1969887535 @default.
• W1729594682 cites W1971873200 @default.
• W1729594682 cites W1981287556 @default.
• W1729594682 cites W1981933466 @default.
• W1729594682 cites W1984503995 @default.
• W1729594682 cites W1988442331 @default.
• W1729594682 cites W2004703623 @default.
• W1729594682 cites W2009253733 @default.
• W1729594682 cites W2040549825 @default.
• W1729594682 cites W2045805632 @default.
• W1729594682 cites W2049730591 @default.
• W1729594682 cites W2055622788 @default.
• W1729594682 cites W2055698029 @default.
• W1729594682 cites W2056168344 @default.
• W1729594682 cites W2083622913 @default.
• W1729594682 cites W2090943591 @default.
• W1729594682 cites W2096212458 @default.
• W1729594682 cites W2096477466 @default.
• W1729594682 cites W2100617045 @default.
• W1729594682 cites W2101422765 @default.
• W1729594682 cites W2102217124 @default.
• W1729594682 cites W2102937009 @default.
• W1729594682 cites W2105747303 @default.
• W1729594682 cites W2106832324 @default.
• W1729594682 cites W2107941964 @default.
• W1729594682 cites W2116710153 @default.
• W1729594682 cites W2120327701 @default.
• W1729594682 cites W2120744835 @default.
• W1729594682 cites W2122648848 @default.
• W1729594682 cites W2129676027 @default.
• W1729594682 cites W2130190391 @default.
• W1729594682 cites W2134606340 @default.
• W1729594682 cites W2144369716 @default.
• W1729594682 cites W2158073865 @default.
• W1729594682 cites W2158950510 @default.
• W1729594682 cites W2165529552 @default.
• W1729594682 cites W2171862804 @default.
• W1729594682 cites W2278413978 @default.
• W1729594682 cites W2317729118 @default.
• W1729594682 cites W4240940294 @default.
• W1729594682 doi "https://doi.org/10.1099/00221287-147-1-97" @default.
• W1729594682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11160804" @default.
• W1729594682 hasPublicationYear "2001" @default.
• W1729594682 type Work @default.
• W1729594682 sameAs 1729594682 @default.
• W1729594682 citedByCount "61" @default.
• W1729594682 countsByYear W17295946822012 @default.
• W1729594682 countsByYear W17295946822013 @default.
• W1729594682 countsByYear W17295946822014 @default.
• W1729594682 countsByYear W17295946822015 @default.
• W1729594682 countsByYear W17295946822016 @default.
• W1729594682 countsByYear W17295946822017 @default.
• W1729594682 countsByYear W17295946822018 @default.
• W1729594682 countsByYear W17295946822021 @default.
• W1729594682 countsByYear W17295946822022 @default.
• W1729594682 crossrefType "journal-article" @default.
• W1729594682 hasAuthorship W1729594682A5019344957 @default.
• W1729594682 hasAuthorship W1729594682A5041019879 @default.
• W1729594682 hasBestOaLocation W17295946821 @default.
• W1729594682 hasConcept C162008176 @default.
• W1729594682 hasConcept C181199279 @default.
• W1729594682 hasConcept C2775838275 @default.
• W1729594682 hasConcept C2776151105 @default.
• W1729594682 hasConcept C2777756538 @default.
• W1729594682 hasConcept C2777979451 @default.
• W1729594682 hasConcept C2778979269 @default.
• W1729594682 hasConcept C2780855054 @default.
• W1729594682 hasConcept C28406088 @default.
• W1729594682 hasConcept C48349386 @default.
• W1729594682 hasConcept C523546767 @default.
• W1729594682 hasConcept C54355233 @default.
• W1729594682 hasConcept C55493867 @default.
• W1729594682 hasConcept C86803240 @default.
• W1729594682 hasConcept C89423630 @default.
• W1729594682 hasConceptScore W1729594682C162008176 @default.
• W1729594682 hasConceptScore W1729594682C181199279 @default.
• W1729594682 hasConceptScore W1729594682C2775838275 @default.

• next