Matches in SemOpenAlex for { <https://semopenalex.org/work/W173070897> ?p ?o ?g. }
- W173070897 endingPage "251" @default.
- W173070897 startingPage "237" @default.
- W173070897 abstract "To compile updated information regarding gonadotropin secretion, specifically the physiology of the midcycle LH surge, in natural cycles and under various ovulation induction protocols. Studies that deal with the clinical aspects of LH surge manipulation or substitution were identified through literature and Medline searches. Three major regulatory factors have been identified as participants in the induction of the midcycle gonadotropin surge. These are hypothalamic GnRH secretion, ovarian and adrenal steroids, and less well-characterized ovarian peptide hormones. Gonadotropin-releasing hormone pulsatility is regulated by a complex mechanism that integrates multiple neurotransmitters and sex steroids. Estradiol plays a central role in the pituitary secretion of LH, which also is influenced by P concentrations. Gonadotropin surge attenuating factor also has been implicated in the regulation of timing and amplitude of the LH surge. Human chorionic gonadotropin is used extensively as a LH surrogate, but its use is associated with a number of disadvantages. Induction of an endogenous LH surge through use of the flare effect of GnRH analogues has been examined more recently and has been found to have several advantages. Recombinant human LH is in the final stages of clinical testing. Although much is known about the physiology of the midcycle LH surge and its variations under different clinical conditions, new approaches to the induction or substitution of the LH surge currently are being examined and learned. The introduction of recombinant gonadotropins into clinical practice is likely to influence ovulation induction and IVF practice to a significant degree in the near future." @default.
- W173070897 created "2016-06-24" @default.
- W173070897 creator A5002465997 @default.
- W173070897 creator A5015512533 @default.
- W173070897 creator A5028575499 @default.
- W173070897 creator A5034927124 @default.
- W173070897 creator A5046189130 @default.
- W173070897 creator A5063773421 @default.
- W173070897 creator A5070737862 @default.
- W173070897 date "1995-08-01" @default.
- W173070897 modified "2023-10-16" @default.
- W173070897 title "The luteinizing hormone surge—the final stage in ovulation induction: modern aspects of ovulation triggering" @default.
- W173070897 cites W124248792 @default.
- W173070897 cites W138858130 @default.
- W173070897 cites W140269156 @default.
- W173070897 cites W1539108320 @default.
- W173070897 cites W1552354325 @default.
- W173070897 cites W158447566 @default.
- W173070897 cites W1764010703 @default.
- W173070897 cites W1915329402 @default.
- W173070897 cites W193561052 @default.
- W173070897 cites W1937631400 @default.
- W173070897 cites W195800306 @default.
- W173070897 cites W1963745146 @default.
- W173070897 cites W1963818126 @default.
- W173070897 cites W1965810610 @default.
- W173070897 cites W1969090164 @default.
- W173070897 cites W1972523938 @default.
- W173070897 cites W1973247872 @default.
- W173070897 cites W1974171474 @default.
- W173070897 cites W1985626390 @default.
- W173070897 cites W1988263837 @default.
- W173070897 cites W1992572347 @default.
- W173070897 cites W1995145782 @default.
- W173070897 cites W1998874154 @default.
- W173070897 cites W1999045306 @default.
- W173070897 cites W2001444544 @default.
- W173070897 cites W2005049371 @default.
- W173070897 cites W2009263708 @default.
- W173070897 cites W2010984948 @default.
- W173070897 cites W2012926829 @default.
- W173070897 cites W2013276719 @default.
- W173070897 cites W2018861564 @default.
- W173070897 cites W2024176341 @default.
- W173070897 cites W2025050579 @default.
- W173070897 cites W2026234932 @default.
- W173070897 cites W2027163344 @default.
- W173070897 cites W2027893657 @default.
- W173070897 cites W2029406824 @default.
- W173070897 cites W2037420362 @default.
- W173070897 cites W2037869461 @default.
- W173070897 cites W2038527370 @default.
- W173070897 cites W2040236308 @default.
- W173070897 cites W2040522155 @default.
- W173070897 cites W2041122938 @default.
- W173070897 cites W2051825905 @default.
- W173070897 cites W2054095576 @default.
- W173070897 cites W2054311107 @default.
- W173070897 cites W2055240421 @default.
- W173070897 cites W2057250907 @default.
- W173070897 cites W2060170224 @default.
- W173070897 cites W2062316204 @default.
- W173070897 cites W2065253899 @default.
- W173070897 cites W2066239285 @default.
- W173070897 cites W2067010841 @default.
- W173070897 cites W2067713504 @default.
- W173070897 cites W2069983396 @default.
- W173070897 cites W2071416461 @default.
- W173070897 cites W2072237396 @default.
- W173070897 cites W2077786605 @default.
- W173070897 cites W2078459968 @default.
- W173070897 cites W2079582382 @default.
- W173070897 cites W2079977461 @default.
- W173070897 cites W2082615720 @default.
- W173070897 cites W2084507289 @default.
- W173070897 cites W2085521048 @default.
- W173070897 cites W2085643743 @default.
- W173070897 cites W2085998115 @default.
- W173070897 cites W2086614662 @default.
- W173070897 cites W2086904979 @default.
- W173070897 cites W2087861136 @default.
- W173070897 cites W2093755058 @default.
- W173070897 cites W2098345439 @default.
- W173070897 cites W2101604598 @default.
- W173070897 cites W2107355555 @default.
- W173070897 cites W2108819835 @default.
- W173070897 cites W2110538681 @default.
- W173070897 cites W2115172949 @default.
- W173070897 cites W2137934764 @default.
- W173070897 cites W2153177934 @default.
- W173070897 cites W2155796235 @default.
- W173070897 cites W2155995048 @default.
- W173070897 cites W2160972227 @default.
- W173070897 cites W2165434804 @default.
- W173070897 cites W2168606645 @default.
- W173070897 cites W2169078557 @default.
- W173070897 cites W2171733778 @default.
- W173070897 cites W2174028974 @default.