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- W1730883952 abstract "Research into the sleep-wake cycle has provided new treatment targets for patients with insomnia as well as a better understanding of how medications affect sleep processes. Current insomnia medications, including benzodiazepines and nonbenzodiazepines, focus on enhancing sleep-promoting systems through broad antagonism of GABA. Other medications that promote sleep by blocking wake-promoting systems include antidepressants, antipsychotics, and antihistamines, but adverse effects and nonspecific therapeutic effects limit their use. New and emerging insomnia medications are focusing on blocking wake-promoting systems via more selective antagonism of orexin, serotonin, and norepinephrine. These medications may offer improved efficacy with fewer adverse effects." @default.
- W1730883952 created "2016-06-24" @default.
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- W1730883952 date "2015-08-26" @default.
- W1730883952 modified "2023-09-26" @default.
- W1730883952 title "Current, Emerging, and Newly Available Insomnia Medications" @default.
- W1730883952 doi "https://doi.org/10.4088/jcp.14046tx2c" @default.
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