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- W1733980810 abstract "The radiobiological effectiveness of 160 MeV protons was measured relative to -Co y-rays, using Chineee hamster cells cultured in o&o. Separate experiments were performed witb cells irradiated in sWpem&m, or attached to plastk tisslre culture flasks. Proton irradiations were performed in the incident plateau of the depth dosepro6Uc~niththeBrPggpenksprendouttocoverlOcls.Inallcrrscstberdstlveblde%esleff~~ (RBE) for protons relative to gamma rays was 1.2 for doses in excess of abont 24M rad. The attswhed cell experiments indkate an in creasing RBE at low doses, whkh is consistent with the microdosimetric measurements. Protons, Bragg peak, Mkrodosimetry, Relative biological effectivpness. IN I’RODUCTION The dose deposited by a proton beam increases with depth. in the exposed medium and reaches a sharp maximum in the region of the Bragg peak, close to the end of the particles’ range. Beyond the particles’ range, the dose becomes very small. By using a proton beam of suitable energy (and therefore range), a tumor volume located at any depth in the body can, in principle, be irradiated precisely and selectively to a high dose, with a minimal dose to the intervening normal tissues and a negligible dose to the deeper tissues. This attractive feature of heavy charged particles, and its potential application to radiotherapy," @default.
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- W1733980810 date "1978-01-01" @default.
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- W1733980810 title "The relative biological effectiveness of 160 MeV protons" @default.
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