Matches in SemOpenAlex for { <https://semopenalex.org/work/W1736189198> ?p ?o ?g. }
- W1736189198 endingPage "290" @default.
- W1736189198 startingPage "243" @default.
- W1736189198 abstract "This chapter presents rhodopsin structure and dynamics at the cytoplasmic face in solution, the comparison between the solution structure and the crystal structure, and the structural changes underlying receptor activation. The data from site-directed spin labeling (SDSL) and disulfide cross-linking together indicate that the crystal and solution structures are very similar at the level of the backbone fold for C1, H8, and the cytoplasmic termination of TM1-TM7. However, substantial differences are seen in C3 and the C-terminal tail, wherein the backbones are flexible on the nanosecond time scale in solution. The chapter also illustrates systematic application of time-resolved SDSL to monitor helix movements, together with the use of chemically modified chromophore structures, is a promising approach to exploring the relationship between chromophore structure, the critical salt bridge, and helix movements leading to activation." @default.
- W1736189198 created "2016-06-24" @default.
- W1736189198 creator A5007619343 @default.
- W1736189198 creator A5010548317 @default.
- W1736189198 creator A5028011181 @default.
- W1736189198 creator A5036133609 @default.
- W1736189198 date "2003-01-01" @default.
- W1736189198 modified "2023-10-14" @default.
- W1736189198 title "Rhodopsin structure, dynamics, and activation: A perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking" @default.
- W1736189198 cites W1544899066 @default.
- W1736189198 cites W1590595627 @default.
- W1736189198 cites W1600771042 @default.
- W1736189198 cites W1858237937 @default.
- W1736189198 cites W1942777601 @default.
- W1736189198 cites W1963932033 @default.
- W1736189198 cites W1975558038 @default.
- W1736189198 cites W1976747271 @default.
- W1736189198 cites W1976862382 @default.
- W1736189198 cites W1978227644 @default.
- W1736189198 cites W1981493123 @default.
- W1736189198 cites W1986568955 @default.
- W1736189198 cites W1988328173 @default.
- W1736189198 cites W1989650576 @default.
- W1736189198 cites W1990129321 @default.
- W1736189198 cites W1991032934 @default.
- W1736189198 cites W1991385639 @default.
- W1736189198 cites W1993343824 @default.
- W1736189198 cites W1994519311 @default.
- W1736189198 cites W1998387435 @default.
- W1736189198 cites W1998767084 @default.
- W1736189198 cites W2000931780 @default.
- W1736189198 cites W2001020509 @default.
- W1736189198 cites W2002060596 @default.
- W1736189198 cites W2002523841 @default.
- W1736189198 cites W2010137450 @default.
- W1736189198 cites W2012470721 @default.
- W1736189198 cites W2012925002 @default.
- W1736189198 cites W2016909839 @default.
- W1736189198 cites W2017754384 @default.
- W1736189198 cites W2019285341 @default.
- W1736189198 cites W2019742616 @default.
- W1736189198 cites W2020031720 @default.
- W1736189198 cites W2027354448 @default.
- W1736189198 cites W2030185192 @default.
- W1736189198 cites W2036379629 @default.
- W1736189198 cites W2036474910 @default.
- W1736189198 cites W2036611025 @default.
- W1736189198 cites W2041843731 @default.
- W1736189198 cites W2042055311 @default.
- W1736189198 cites W2042307676 @default.
- W1736189198 cites W2043393099 @default.
- W1736189198 cites W2043774431 @default.
- W1736189198 cites W2044835337 @default.
- W1736189198 cites W2049359390 @default.
- W1736189198 cites W2052998793 @default.
- W1736189198 cites W2057620252 @default.
- W1736189198 cites W2061373719 @default.
- W1736189198 cites W2066109743 @default.
- W1736189198 cites W2066769462 @default.
- W1736189198 cites W2067106661 @default.
- W1736189198 cites W2067382519 @default.
- W1736189198 cites W2068077460 @default.
- W1736189198 cites W2068370755 @default.
- W1736189198 cites W2069865904 @default.
- W1736189198 cites W2069888185 @default.
- W1736189198 cites W2073690777 @default.
- W1736189198 cites W2078122870 @default.
- W1736189198 cites W2083637735 @default.
- W1736189198 cites W2085616004 @default.
- W1736189198 cites W2086056683 @default.
- W1736189198 cites W2086868295 @default.
- W1736189198 cites W2089090006 @default.
- W1736189198 cites W2089189332 @default.
- W1736189198 cites W2090020265 @default.
- W1736189198 cites W2090678119 @default.
- W1736189198 cites W2092054802 @default.
- W1736189198 cites W2093182897 @default.
- W1736189198 cites W2104084043 @default.
- W1736189198 cites W2125468282 @default.
- W1736189198 cites W2128677332 @default.
- W1736189198 cites W2130049582 @default.
- W1736189198 cites W2133524076 @default.
- W1736189198 cites W2140686653 @default.
- W1736189198 cites W2146048430 @default.
- W1736189198 cites W2149963584 @default.
- W1736189198 cites W2154612934 @default.
- W1736189198 cites W2154631708 @default.
- W1736189198 cites W2155584072 @default.
- W1736189198 cites W2157724269 @default.
- W1736189198 cites W2163607652 @default.
- W1736189198 cites W2164192718 @default.
- W1736189198 cites W2187466185 @default.
- W1736189198 cites W2372235053 @default.
- W1736189198 cites W2414461651 @default.
- W1736189198 cites W4246584994 @default.
- W1736189198 doi "https://doi.org/10.1016/s0065-3233(03)63010-x" @default.
- W1736189198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12629973" @default.
- W1736189198 hasPublicationYear "2003" @default.