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- W173632708 abstract "Invertebrates comprise the vast majority of contemporary animal species, yet their immune system been poorly characterized, especially at the molecular level (Klein, 1995). Nevertheless, invertebrates possess elaborate mechanisms to identify and eliminate life-threatening pathogens (reviews by: Smith and Davidson, 1992; Sima, 1993; Smith and Davidson, 1994; Hoffmann et al., 1996; Medzhitov and Janeway, 1998). While the evolutionary elaboration of anti-pathogen responses in a hostile environment seems inevitable, the evolution of invertebrate and vertebrate individuality determining systems presents an evolutionary enigma. A basic function of the vertebrate immune system is to maintain a representative “image” of the cells and molecules of which individuals consist, and to mediate in the conflict between cooperation and competition among individual cells. The development and elaboration of such molecular and cellular surveillance systems might have accompanied the emergence of multicellular animals, along with the evolution of higher levels of molecular and cellular complexity." @default.
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- W173632708 date "2001-01-01" @default.
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- W173632708 title "Individual-Specific Repertoires of Immune Cells SRCR Receptors in the Purple Sea Urchin(S. Purpuratus)" @default.
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- W173632708 doi "https://doi.org/10.1007/978-1-4615-1291-2_3" @default.
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