Matches in SemOpenAlex for { <https://semopenalex.org/work/W17364042> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W17364042 endingPage "6" @default.
- W17364042 startingPage "1052" @default.
- W17364042 abstract "Nine Holstein-Friesian cows in the same stage of lactation were randomly given IM injections of saline solution, 100 IU of ACTH, or 200 IU of ACTH for a period of 3 days at 0800 and 1600 hours on one day and at 0100 hours the next day. A dose of 100 IU of ACTH represented the amount of ACTH released during physiologic stress and 200 IU of ACTH represented a therapeutic dose. Blood samples were obtained from indwelling jugular catheters for total circulating leukocyte and total plasma corticosteroid determinations at -1, 0, 0.25, 0.50, 1, 1.50, 2, 4, 6, and 8 hours after the 0800-hour ACTH injections. Concentrations of blood leukocytes and total plasma corticosteroids were affected significantly (P < 0.05) by treatment, cow within treatment, day of injection, treatment by day interaction, time, treatment by time interaction, and day by time interaction. Total plasma corticosteroids were 5.6 ng/ml (saline), 38.9 ng/ml (100 IU of ACTH), and 59.8 ng/ml (200 IU of ACTH). Mean corticosteroid concentrations from 0.5 to 8 hours were 29.2 ng/ml on day 1, 42.5 ng/ml on day 2, and 32.7 ng/ml on day 3. Blood leukocytes were 8,545 cells/mm3 (saline, 11,241 cells/mm3 (100 IU of ACTH) and 9,777 cells/mm3 (200 IU of ACTH). When compared with basal circulating leukocyte concentrations (within cow), this represented increases of 20.7% for 100 IU of ACTH and 24.5% for 200 IU. Mean circulating leukocyte concentrations from 0.5 to 8 hours were 8,900 cells/mm3 on day 1, 10,500 cells/mm3 on day 2, and 10,000 cells/mm3 on day 3. These data indicate that the adrenal gland responded less on day 3 and that continuous stimulation of bovine adrenal glands by ACTH at physiologic and therapeutic concentration could lead to reduced synthesis or release of adrenal corticosteroids (or both) with concomitant reduction in the concentration of total circulating leukocytes." @default.
- W17364042 created "2016-06-24" @default.
- W17364042 creator A5013711186 @default.
- W17364042 creator A5020498509 @default.
- W17364042 creator A5079570045 @default.
- W17364042 creator A5086039818 @default.
- W17364042 date "1980-07-01" @default.
- W17364042 modified "2023-10-14" @default.
- W17364042 title "Plasma glucocorticoid and circulating blood leukocyte responses in cattle after sequential intramuscular injections of ACTH." @default.
- W17364042 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6254408" @default.
- W17364042 hasPublicationYear "1980" @default.
- W17364042 type Work @default.
- W17364042 sameAs 17364042 @default.
- W17364042 citedByCount "22" @default.
- W17364042 countsByYear W173640422015 @default.
- W17364042 countsByYear W173640422018 @default.
- W17364042 crossrefType "journal-article" @default.
- W17364042 hasAuthorship W17364042A5013711186 @default.
- W17364042 hasAuthorship W17364042A5020498509 @default.
- W17364042 hasAuthorship W17364042A5079570045 @default.
- W17364042 hasAuthorship W17364042A5086039818 @default.
- W17364042 hasConcept C126322002 @default.
- W17364042 hasConcept C134018914 @default.
- W17364042 hasConcept C2776804153 @default.
- W17364042 hasConcept C2777397205 @default.
- W17364042 hasConcept C2778024521 @default.
- W17364042 hasConcept C2779306644 @default.
- W17364042 hasConcept C2780546910 @default.
- W17364042 hasConcept C2780841215 @default.
- W17364042 hasConcept C71315377 @default.
- W17364042 hasConcept C71924100 @default.
- W17364042 hasConceptScore W17364042C126322002 @default.
- W17364042 hasConceptScore W17364042C134018914 @default.
- W17364042 hasConceptScore W17364042C2776804153 @default.
- W17364042 hasConceptScore W17364042C2777397205 @default.
- W17364042 hasConceptScore W17364042C2778024521 @default.
- W17364042 hasConceptScore W17364042C2779306644 @default.
- W17364042 hasConceptScore W17364042C2780546910 @default.
- W17364042 hasConceptScore W17364042C2780841215 @default.
- W17364042 hasConceptScore W17364042C71315377 @default.
- W17364042 hasConceptScore W17364042C71924100 @default.
- W17364042 hasIssue "7" @default.
- W17364042 hasLocation W173640421 @default.
- W17364042 hasOpenAccess W17364042 @default.
- W17364042 hasPrimaryLocation W173640421 @default.
- W17364042 hasRelatedWork W17364042 @default.
- W17364042 hasRelatedWork W1992451430 @default.
- W17364042 hasRelatedWork W2007827519 @default.
- W17364042 hasRelatedWork W2049825494 @default.
- W17364042 hasRelatedWork W2063972305 @default.
- W17364042 hasRelatedWork W2078757988 @default.
- W17364042 hasRelatedWork W2114213264 @default.
- W17364042 hasRelatedWork W2119037360 @default.
- W17364042 hasRelatedWork W2271467258 @default.
- W17364042 hasRelatedWork W3109863692 @default.
- W17364042 hasVolume "41" @default.
- W17364042 isParatext "false" @default.
- W17364042 isRetracted "false" @default.
- W17364042 magId "17364042" @default.
- W17364042 workType "article" @default.