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• W173710865 abstract "Abstract Glanzmann's thrombasthenia is a bleeding disorder, inherited in an autosomal recessive way and characterized by an absence or deficiency of the platelet glycoprotein (GP) IIb/IIIa complex. Recently, we and others demonstrated that cultured human umbilical vein endothelial cells synthesized a membrane protein complex similar to the platelet GP IIb/IIIa complex. In this article, we demonstrate that endothelial cells isolated from the umbilical vein of a newborn with Glanzmann's thrombasthenia, as compared with normal endothelial cells, show no difference in their ability to synthesize and express this GP IIb/IIIa complex. Our results indicate that Glanzmann's thrombasthenia is not accompanied by an “endotheliopathy.”" @default.
• W173710865 created "2016-06-24" @default.
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• W173710865 date "1987-03-01" @default.
• W173710865 modified "2023-09-27" @default.
• W173710865 title "Normal synthesis and expression of endothelial IIb/IIIa in Glanzmann's thrombasthenia" @default.
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• W173710865 doi "https://doi.org/10.1182/blood.v69.3.809.809" @default.
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