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- W1737223868 endingPage "1034" @default.
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- W1737223868 abstract "Drug repositioning and similar terms have been a trending topic in literature and represent novel drug development strategies. We analysed in a quantitative and qualitative manner how these terms were used and defined in the literature. In total, 217 articles referred to 'drug repositioning', 'drug repurposing', 'drug reprofiling', 'drug redirecting' and/or 'drug rediscovery'. Only 67 included a definition ranging from brief and general to extensive and specific. No common definition was identified. Nevertheless, four common features were found: concept, action, use and product. The different wording used for these features often leads to essential differences in meaning between definitions. In case a clear definition is needed, for example from a legal or regulatory perspective, the features can provide further guidance." @default.
- W1737223868 created "2016-06-24" @default.
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- W1737223868 creator A5041722553 @default.
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- W1737223868 date "2015-08-01" @default.
- W1737223868 modified "2023-10-08" @default.
- W1737223868 title "Drug repositioning and repurposing: terminology and definitions in literature" @default.
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- W1737223868 doi "https://doi.org/10.1016/j.drudis.2015.05.001" @default.
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