FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1738144688> ?p ?o ?g. }

• W1738144688 endingPage "5519" @default.
• W1738144688 startingPage "5513" @default.
• W1738144688 abstract "This study examined the role of the mitogen-activated protein kinase (MAPK) family during acquisition of the rabbit's classically conditioned eye-blink response. Eye-blink conditioning produced a significant, bilateral activation of both extracellular signal-regulated protein kinases (ERKs) and p38 MAPK in the anterior cerebellar vermis. There was also a significant bilateral activation of ERKs in the dorsal hippocampus with no change in p38 MAPK. These changes were seen at 2 min after the last conditioning session, were maintained for at least 180 min, and occurred without any change in the protein expression of either ERKs or p38 MAPK. There were no changes in ERKs or p38 MAPK in frontal cortex, in cerebellar hemispheral lobule VI, or in a section of brainstem containing the inferior olive. Moreover, the stress-related protein kinase Jun N-terminal kinase (JNK), another subfamily of MAPKs, was not altered in any of the brain regions examined. Animals receiving explicitly unpaired presentations of a conditioned stimulus and an unconditioned stimulus did not acquire conditioned responses (CRs) and did not demonstrate any changes in ERKs, p38 MAPK, or JNK. The intraventricular injection of SB203580, a selective p38 MAPK inhibitor, significantly retarded CR acquisition and blocked the learning-related increases in p38 MAPK activity in the anterior vermis. PD98059, a selective MAPK kinase inhibitor, had a smaller and only marginally significant effect on CR acquisition, although it did block the learning-related increases in ERK activity in both the hippocampus and anterior vermis. These results indicate that p38 MAPK is activated during associative learning and may play a role in the transcriptional events that lead to memory consolidation." @default.
• W1738144688 created "2016-06-24" @default.
• W1738144688 creator A5006108739 @default.
• W1738144688 creator A5027189606 @default.
• W1738144688 creator A5031247002 @default.
• W1738144688 creator A5050058361 @default.
• W1738144688 creator A5064734707 @default.
• W1738144688 date "2001-08-01" @default.
• W1738144688 modified "2023-10-17" @default.
• W1738144688 title "The p38 Mitogen-Activated Protein Kinase Is Involved in Associative Learning in Rabbits" @default.
• W1738144688 cites W1573821584 @default.
• W1738144688 cites W1579779680 @default.
• W1738144688 cites W1639247045 @default.
• W1738144688 cites W1968064081 @default.
• W1738144688 cites W1974011436 @default.
• W1738144688 cites W1974084880 @default.
• W1738144688 cites W1993037321 @default.
• W1738144688 cites W1999808638 @default.
• W1738144688 cites W2005913098 @default.
• W1738144688 cites W2011194016 @default.
• W1738144688 cites W2015592781 @default.
• W1738144688 cites W2017169966 @default.
• W1738144688 cites W2018813678 @default.
• W1738144688 cites W2020317154 @default.
• W1738144688 cites W2023208205 @default.
• W1738144688 cites W2025198517 @default.
• W1738144688 cites W2026490200 @default.
• W1738144688 cites W2026715748 @default.
• W1738144688 cites W2032413323 @default.
• W1738144688 cites W2041894539 @default.
• W1738144688 cites W2054547362 @default.
• W1738144688 cites W2058963528 @default.
• W1738144688 cites W2068787204 @default.
• W1738144688 cites W2087973535 @default.
• W1738144688 cites W2101626807 @default.
• W1738144688 cites W2101683407 @default.
• W1738144688 cites W2112251100 @default.
• W1738144688 cites W2117862683 @default.
• W1738144688 cites W2120160609 @default.
• W1738144688 cites W2122972611 @default.
• W1738144688 cites W2132802598 @default.
• W1738144688 cites W2138474942 @default.
• W1738144688 cites W2141014036 @default.
• W1738144688 cites W2150666125 @default.
• W1738144688 cites W2162836049 @default.
• W1738144688 cites W2340064264 @default.
• W1738144688 cites W2425949837 @default.
• W1738144688 cites W3171415558 @default.
• W1738144688 doi "https://doi.org/10.1523/jneurosci.21-15-05513.2001" @default.
• W1738144688 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6762655" @default.
• W1738144688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11466422" @default.
• W1738144688 hasPublicationYear "2001" @default.
• W1738144688 type Work @default.
• W1738144688 sameAs 1738144688 @default.
• W1738144688 citedByCount "59" @default.
• W1738144688 countsByYear W17381446882012 @default.
• W1738144688 countsByYear W17381446882014 @default.
• W1738144688 countsByYear W17381446882015 @default.
• W1738144688 countsByYear W17381446882016 @default.
• W1738144688 countsByYear W17381446882017 @default.
• W1738144688 countsByYear W17381446882019 @default.
• W1738144688 countsByYear W17381446882021 @default.
• W1738144688 countsByYear W17381446882022 @default.
• W1738144688 countsByYear W17381446882023 @default.
• W1738144688 crossrefType "journal-article" @default.
• W1738144688 hasAuthorship W1738144688A5006108739 @default.
• W1738144688 hasAuthorship W1738144688A5027189606 @default.
• W1738144688 hasAuthorship W1738144688A5031247002 @default.
• W1738144688 hasAuthorship W1738144688A5050058361 @default.
• W1738144688 hasAuthorship W1738144688A5064734707 @default.
• W1738144688 hasBestOaLocation W17381446881 @default.
• W1738144688 hasConcept C126322002 @default.
• W1738144688 hasConcept C134018914 @default.
• W1738144688 hasConcept C15744967 @default.
• W1738144688 hasConcept C169760540 @default.
• W1738144688 hasConcept C184235292 @default.
• W1738144688 hasConcept C185592680 @default.
• W1738144688 hasConcept C51551487 @default.
• W1738144688 hasConcept C55493867 @default.
• W1738144688 hasConcept C57074206 @default.
• W1738144688 hasConcept C71924100 @default.
• W1738144688 hasConcept C86803240 @default.
• W1738144688 hasConcept C97029542 @default.
• W1738144688 hasConceptScore W1738144688C126322002 @default.
• W1738144688 hasConceptScore W1738144688C134018914 @default.
• W1738144688 hasConceptScore W1738144688C15744967 @default.
• W1738144688 hasConceptScore W1738144688C169760540 @default.
• W1738144688 hasConceptScore W1738144688C184235292 @default.
• W1738144688 hasConceptScore W1738144688C185592680 @default.
• W1738144688 hasConceptScore W1738144688C51551487 @default.
• W1738144688 hasConceptScore W1738144688C55493867 @default.
• W1738144688 hasConceptScore W1738144688C57074206 @default.
• W1738144688 hasConceptScore W1738144688C71924100 @default.
• W1738144688 hasConceptScore W1738144688C86803240 @default.
• W1738144688 hasConceptScore W1738144688C97029542 @default.
• W1738144688 hasIssue "15" @default.
• W1738144688 hasLocation W17381446881 @default.
• W1738144688 hasLocation W17381446882 @default.

• next