FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1738194614> ?p ?o ?g. }

• W1738194614 endingPage "1020" @default.
• W1738194614 startingPage "1016" @default.
• W1738194614 abstract "Genetic factors have been implicated in the etiology of inflammatory bowel disease (IBD) because of the increased occurrence of IBD in relatives. To further characterize the familial aggregation of IBD, we obtained family histories by interview on 188 IBD patients, including 154 Ashkenazi Jews (82%), ascertained through a Los Angeles gastroenterology practice. Thirty-three index cases (17.6%) had at least one affected first-degree relative; an additional 11 had more distant affected relatives. Thus, 23.4% of our sample had a positive family history. The quantification of empiric risk estimates for various classes of relatives has been quite limited and has been reported in only a few series. An important goal of our study was the determination of the specific empiric risk figures for relatives. We obtained uncorrected risk estimates of 2.5% to off-spring, 5.2% to siblings, and 2.9% to parents. Although the highest risk we observed is to siblings, IBD has a variable and often late age of onset, and it is likely that many relatives, particularly offspring, of patients in this sample have not reached the age at which they will manifest clinical disease. Thus, these uncorrected risks as well as those reported in the literature are an underestimate of the true empiric risks. To provide an estimate of the true lifetime risks, we utilized age-specific incidence data to calculate the following age-corrected empiric risk estimates for IBD: 8.9% to offspring, 8.8% to siblings, and 3.5% to parents. It is these latter age-corrected estimates that are most appropriate for both genetic counseling and genetic modeling." @default.
• W1738194614 created "2016-06-24" @default.
• W1738194614 creator A5008136673 @default.
• W1738194614 creator A5011161087 @default.
• W1738194614 creator A5014268065 @default.
• W1738194614 creator A5040770914 @default.
• W1738194614 creator A5048782070 @default.
• W1738194614 creator A5057809095 @default.
• W1738194614 date "1989-04-01" @default.
• W1738194614 modified "2023-09-25" @default.
• W1738194614 title "Familial empiric risk estimates of inflammatory bowel disease in Ashkenazi Jews" @default.
• W1738194614 cites W1561588767 @default.
• W1738194614 cites W1803970038 @default.
• W1738194614 cites W1912332982 @default.
• W1738194614 cites W1968499365 @default.
• W1738194614 cites W1975461746 @default.
• W1738194614 cites W1982595467 @default.
• W1738194614 cites W1992266829 @default.
• W1738194614 cites W2001216921 @default.
• W1738194614 cites W2015246046 @default.
• W1738194614 cites W2017264266 @default.
• W1738194614 cites W2038987878 @default.
• W1738194614 cites W2041244282 @default.
• W1738194614 cites W2052540596 @default.
• W1738194614 cites W2071774207 @default.
• W1738194614 cites W2077198680 @default.
• W1738194614 cites W2085940317 @default.
• W1738194614 cites W2087260833 @default.
• W1738194614 cites W2091214043 @default.
• W1738194614 cites W2092623157 @default.
• W1738194614 cites W2095584031 @default.
• W1738194614 cites W2130241188 @default.
• W1738194614 cites W2139987412 @default.
• W1738194614 cites W2255852711 @default.
• W1738194614 cites W2406842912 @default.
• W1738194614 cites W2439513538 @default.
• W1738194614 cites W3160068681 @default.
• W1738194614 cites W4211119833 @default.
• W1738194614 cites W4300463635 @default.
• W1738194614 cites W4300852529 @default.
• W1738194614 doi "https://doi.org/10.1016/0016-5085(89)91618-1" @default.
• W1738194614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2925048" @default.
• W1738194614 hasPublicationYear "1989" @default.
• W1738194614 type Work @default.
• W1738194614 sameAs 1738194614 @default.
• W1738194614 citedByCount "154" @default.
• W1738194614 countsByYear W17381946142012 @default.
• W1738194614 countsByYear W17381946142013 @default.
• W1738194614 countsByYear W17381946142014 @default.
• W1738194614 countsByYear W17381946142015 @default.
• W1738194614 countsByYear W17381946142016 @default.
• W1738194614 countsByYear W17381946142017 @default.
• W1738194614 countsByYear W17381946142018 @default.
• W1738194614 countsByYear W17381946142019 @default.
• W1738194614 countsByYear W17381946142021 @default.
• W1738194614 countsByYear W17381946142022 @default.
• W1738194614 crossrefType "journal-article" @default.
• W1738194614 hasAuthorship W1738194614A5008136673 @default.
• W1738194614 hasAuthorship W1738194614A5011161087 @default.
• W1738194614 hasAuthorship W1738194614A5014268065 @default.
• W1738194614 hasAuthorship W1738194614A5040770914 @default.
• W1738194614 hasAuthorship W1738194614A5048782070 @default.
• W1738194614 hasAuthorship W1738194614A5057809095 @default.
• W1738194614 hasConcept C107130276 @default.
• W1738194614 hasConcept C112672928 @default.
• W1738194614 hasConcept C120665830 @default.
• W1738194614 hasConcept C121332964 @default.
• W1738194614 hasConcept C126322002 @default.
• W1738194614 hasConcept C137627325 @default.
• W1738194614 hasConcept C144024400 @default.
• W1738194614 hasConcept C149923435 @default.
• W1738194614 hasConcept C187212893 @default.
• W1738194614 hasConcept C2778260677 @default.
• W1738194614 hasConcept C2779134260 @default.
• W1738194614 hasConcept C2779234561 @default.
• W1738194614 hasConcept C2779862289 @default.
• W1738194614 hasConcept C2781179581 @default.
• W1738194614 hasConcept C54355233 @default.
• W1738194614 hasConcept C61511704 @default.
• W1738194614 hasConcept C71924100 @default.
• W1738194614 hasConcept C86803240 @default.
• W1738194614 hasConceptScore W1738194614C107130276 @default.
• W1738194614 hasConceptScore W1738194614C112672928 @default.
• W1738194614 hasConceptScore W1738194614C120665830 @default.
• W1738194614 hasConceptScore W1738194614C121332964 @default.
• W1738194614 hasConceptScore W1738194614C126322002 @default.
• W1738194614 hasConceptScore W1738194614C137627325 @default.
• W1738194614 hasConceptScore W1738194614C144024400 @default.
• W1738194614 hasConceptScore W1738194614C149923435 @default.
• W1738194614 hasConceptScore W1738194614C187212893 @default.
• W1738194614 hasConceptScore W1738194614C2778260677 @default.
• W1738194614 hasConceptScore W1738194614C2779134260 @default.
• W1738194614 hasConceptScore W1738194614C2779234561 @default.
• W1738194614 hasConceptScore W1738194614C2779862289 @default.
• W1738194614 hasConceptScore W1738194614C2781179581 @default.
• W1738194614 hasConceptScore W1738194614C54355233 @default.
• W1738194614 hasConceptScore W1738194614C61511704 @default.
• W1738194614 hasConceptScore W1738194614C71924100 @default.

• next