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- W173844744 abstract "The present chapter considers the acute haemodynamic effects of calcium channel blockers. Although those agents are used in therapy for long-term (even life-long) treatment, it is of interest to examine the acute haemodynamic changes evoked when those agents are administered at pharmacologically active doses. Such a study allows comparing the various CCBs from a functional point of view considering potency, pharmacokinetics and tissue selectivity. The examples taken in this section are illustrative of the actions of CCBs in general, even if all drugs have not been examined. Owing the complexity of haemodynamic reflexes and the tissue selectivity of CCBs at the level of the various vascular beds, it may be anticipated that those drugs may exhibit variations in action according to the vascular bed or the species so far considered. Because of the importance of CCBs for the therapy of coronary diseases, hypertension and stroke, their action has been studied in coronary, renal and cerebral circulations." @default.
- W173844744 created "2016-06-24" @default.
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- W173844744 date "2004-01-01" @default.
- W173844744 modified "2023-10-17" @default.
- W173844744 title "Acute haemodynamic effects of calcium channel blockers" @default.
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- W173844744 doi "https://doi.org/10.1007/978-3-0348-7859-3_5" @default.
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