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- W1738580061 abstract "Due to its large molecular weight trastuzumab is easily blocked by the intact blood brain-barrier or even when it's partly impaired in meningeal carcinomatosis or brain metastasis. Its penetration is facilitated by whole-brain-radiotherapy but trastuzumab only reaches rather low and most likely therapeutically inadequate levels in central nervous system after intravenous application. Further investigations with lapatinib are warrented." @default.
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- W1738580061 title "[Trastuzumab and blood-brain barrier]" @default.
- W1738580061 doi "https://doi.org/10.1684/bdc.2007.0486" @default.
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