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- W173892716 abstract "82 consecutive patients on continous lithium treatment checked at the out-patient clinic of the psychiatry department of the Umeå university were typed for HLA-anti-gens. By comparing the group of those who did not relapse on lithium therapy (n=48) with the group of those who did relapse (n=34) there was a significant higher frequency of the HLA-A3 antigen among those who did relapse, and none of those who did not relapse was found to have the HLA-B18 antigen. In 42 patients the RBC/plasma lithium ratio has also been calculated. When the patients in this latter series were divided into two groups above and below the median value of the RBC/plasma ratio, a heterogeneity among the groups as regards the antigens B35 and B40 emerged. The results suggest a possible interference between HLA-antigens and response to lithium treatment." @default.
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- W173892716 date "1979-01-01" @default.
- W173892716 modified "2023-09-26" @default.
- W173892716 title "Genetic Components in the Mechanism of Action of Lithium: HLA-Antigens and the Response to Prophylactic Lithium" @default.
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- W173892716 doi "https://doi.org/10.1016/b978-0-08-023089-4.50013-2" @default.
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