Matches in SemOpenAlex for { <https://semopenalex.org/work/W1742563376> ?p ?o ?g. }
- W1742563376 endingPage "12" @default.
- W1742563376 startingPage "1" @default.
- W1742563376 abstract "Alpha lipoic acid (ALA), an active substance in anti-aging products and dietary supplements, need to be masked with an edible polymer to obscure its unpleasant taste. However, the high viscosity of the ALA molecules prevents them from forming microcomposites with masking materials even in supercritical carbon dioxide (scCO2). Therefore, the purpose of this study was to investigate and develop a novel production method for microcomposite particles for ALA in hydrogenated colza oil (HCO). Microcomposite particles of ALA/HCO were prepared by using a novel gas-saturated solution (PGSS) process in which the solid-dispersion method is used along with stepwise temperature control (PGSS-STC). Its high viscosity prevents the formation of microcomposites in the conventional PGSS process even under strong agitation. Here, we disperse the solid particles of ALA and HCO in scCO2 at low temperatures and change the temperature stepwise in order to mix the melted ALA and HCO in scCO2. As a result, a homogeneous dispersion of the droplets of ALA in melted HCO saturated with CO2 is obtained at high temperatures. After the rapid expansion of the saturated solution through a nozzle, microcomposite particles of ALA/HCO several micrometers in diameter are obtained." @default.
- W1742563376 created "2016-06-24" @default.
- W1742563376 creator A5006665177 @default.
- W1742563376 creator A5024025174 @default.
- W1742563376 creator A5025605459 @default.
- W1742563376 creator A5026372549 @default.
- W1742563376 creator A5027327792 @default.
- W1742563376 creator A5031092004 @default.
- W1742563376 creator A5051884988 @default.
- W1742563376 creator A5053930938 @default.
- W1742563376 creator A5067858921 @default.
- W1742563376 creator A5079169974 @default.
- W1742563376 creator A5081767468 @default.
- W1742563376 creator A5083283148 @default.
- W1742563376 creator A5084848990 @default.
- W1742563376 creator A5089364503 @default.
- W1742563376 creator A5091590042 @default.
- W1742563376 date "2015-05-29" @default.
- W1742563376 modified "2023-10-18" @default.
- W1742563376 title "Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide" @default.
- W1742563376 cites W1971345094 @default.
- W1742563376 cites W1971829617 @default.
- W1742563376 cites W1972382060 @default.
- W1742563376 cites W1977624094 @default.
- W1742563376 cites W1979086031 @default.
- W1742563376 cites W1984599826 @default.
- W1742563376 cites W1985870571 @default.
- W1742563376 cites W1986664142 @default.
- W1742563376 cites W1992461918 @default.
- W1742563376 cites W1994229892 @default.
- W1742563376 cites W1995008519 @default.
- W1742563376 cites W2000945001 @default.
- W1742563376 cites W2006099179 @default.
- W1742563376 cites W2008278499 @default.
- W1742563376 cites W2008418938 @default.
- W1742563376 cites W2011769997 @default.
- W1742563376 cites W2013693616 @default.
- W1742563376 cites W2016381215 @default.
- W1742563376 cites W2017056896 @default.
- W1742563376 cites W2017316559 @default.
- W1742563376 cites W2020331396 @default.
- W1742563376 cites W2028308584 @default.
- W1742563376 cites W2030414350 @default.
- W1742563376 cites W2035504806 @default.
- W1742563376 cites W2040550121 @default.
- W1742563376 cites W2041786506 @default.
- W1742563376 cites W2043848754 @default.
- W1742563376 cites W2045079377 @default.
- W1742563376 cites W2046278636 @default.
- W1742563376 cites W2053946449 @default.
- W1742563376 cites W2059430101 @default.
- W1742563376 cites W2062367619 @default.
- W1742563376 cites W2063046339 @default.
- W1742563376 cites W2065254628 @default.
- W1742563376 cites W2065523790 @default.
- W1742563376 cites W2066274443 @default.
- W1742563376 cites W2067650133 @default.
- W1742563376 cites W2071602058 @default.
- W1742563376 cites W2079268420 @default.
- W1742563376 cites W2085113776 @default.
- W1742563376 cites W2087922313 @default.
- W1742563376 cites W2093505255 @default.
- W1742563376 cites W2095037914 @default.
- W1742563376 cites W2099656568 @default.
- W1742563376 cites W2110607710 @default.
- W1742563376 cites W2124348797 @default.
- W1742563376 cites W2128909673 @default.
- W1742563376 cites W2135008825 @default.
- W1742563376 cites W2153800384 @default.
- W1742563376 cites W2159432191 @default.
- W1742563376 cites W2160661390 @default.
- W1742563376 cites W2162901606 @default.
- W1742563376 cites W2313638148 @default.
- W1742563376 doi "https://doi.org/10.3109/10837450.2015.1049707" @default.
- W1742563376 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26024240" @default.
- W1742563376 hasPublicationYear "2015" @default.
- W1742563376 type Work @default.
- W1742563376 sameAs 1742563376 @default.
- W1742563376 citedByCount "4" @default.
- W1742563376 countsByYear W17425633762016 @default.
- W1742563376 countsByYear W17425633762021 @default.
- W1742563376 countsByYear W17425633762022 @default.
- W1742563376 countsByYear W17425633762023 @default.
- W1742563376 crossrefType "journal-article" @default.
- W1742563376 hasAuthorship W1742563376A5006665177 @default.
- W1742563376 hasAuthorship W1742563376A5024025174 @default.
- W1742563376 hasAuthorship W1742563376A5025605459 @default.
- W1742563376 hasAuthorship W1742563376A5026372549 @default.
- W1742563376 hasAuthorship W1742563376A5027327792 @default.
- W1742563376 hasAuthorship W1742563376A5031092004 @default.
- W1742563376 hasAuthorship W1742563376A5051884988 @default.
- W1742563376 hasAuthorship W1742563376A5053930938 @default.
- W1742563376 hasAuthorship W1742563376A5067858921 @default.
- W1742563376 hasAuthorship W1742563376A5079169974 @default.
- W1742563376 hasAuthorship W1742563376A5081767468 @default.
- W1742563376 hasAuthorship W1742563376A5083283148 @default.
- W1742563376 hasAuthorship W1742563376A5084848990 @default.
- W1742563376 hasAuthorship W1742563376A5089364503 @default.