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- W174307561 abstract "This chapter describes the prevention of osteoporosis, that is, the most common abnormality of the adult skeleton. The diagnosis of osteoporosis initially rests upon establishing adequate radiological criteria to substantiate a deficiency of bone substance. The appearance of radio translucency of the skeleton is not enough and the diagnosis must be backed up by a quantitative measurement at an appropriate skeletal site. When osteoporosis is generalized, bone mass measurements on peripheral bone sites, where cortical bone predominates, are preferable to measurements on the axial skeleton, where there is a higher proportion of trabecular bone, because the former are amenable to a much greater degree of precision and reproducibility. Hence, trabecular bone, with its high metabolic activity, is lost to a much greater extent than cortical bone in the early stages of generalized skeletal wasting. However, in spite of this initial lack of synchronism between bone loss at trabecular and cortical sites, there is a surprisingly good in vitro correlation in the aging population between measurements of bone mass at sites of widely varying structural composition. The use of synthetic anabolic steroids, such as androgens and anabolic, are used for the treatment of osteoporosis, but they are considerably less effective than oestrogens in the prevention of further spinal collapse in postmenopausal women. However, the prevention of osteoporosis caused by sex hormone deficiency could be theoretically simple if all postmenopausal women are to be assessed for sex hormone replacement therapy." @default.
- W174307561 created "2016-06-24" @default.
- W174307561 creator A5064453919 @default.
- W174307561 date "1982-01-01" @default.
- W174307561 modified "2023-10-14" @default.
- W174307561 title "The prevention of osteoporosis" @default.
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