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- W1744006947 abstract "Nijiro Nohata 1,2 , Toyoyuki Hanazawa 2 , Hideki Enokida 3 , Naohiko Seki 1 1 Department of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan 2 Department of Otorhinolaryngology/Head and Neck Surgery, Chiba University Graduate School of Medicine, Chiba, Japan 3 Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan Received: January 25, 2012; Accepted: January 25, 2012; Published: February 4, 2012; Keywords: cancer, miRNA, miR-1, miR-133a, miR-133b, miR-206 Correspondence: Naohiko Seki, email: // // Abstract MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene expression by repressing translation or cleaving RNA transcripts in a sequence-specific manner. A growing body of evidence suggests that miRNAs are aberrantly expressed in many human cancers and that they play significant roles in the initiation, development and metastasis of human cancers. Genome-wide miRNA expression signatures provide information on the aberrant expression of miRNAs in cancers rapidly and precisely. Recently, studies from our group and others revealed that microRNA-1 (miR-1), microRNA-133a (miR-133a), microRNA-133b (miR-133b) and microRNA-206 (miR-206) are frequently downregulated in various types of cancers. Interestingly, miR-1-1/miR-133a-2, miR-1-2/miR-133a-1, and miR-206/miR-133b form clusters in three different chromosomal regions of the human genome – 20q13.33, 18q11.2 and 6p12.1, respectively. Here we review highlights of recent findings on the aberrant expression and functional significance of the miR-1/miR-133a and miR-206/miR-133b clusters in human cancers." @default.
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- W1744006947 date "2012-01-31" @default.
- W1744006947 modified "2023-10-01" @default.
- W1744006947 title "microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers" @default.
- W1744006947 cites W144423133 @default.
- W1744006947 cites W1648301895 @default.
- W1744006947 cites W1866072251 @default.
- W1744006947 cites W1917706778 @default.
- W1744006947 cites W1964496783 @default.
- W1744006947 cites W1966566182 @default.
- W1744006947 cites W1966749076 @default.
- W1744006947 cites W1967832728 @default.
- W1744006947 cites W1970137304 @default.
- W1744006947 cites W1970907985 @default.
- W1744006947 cites W1975303273 @default.
- W1744006947 cites W1975437957 @default.
- W1744006947 cites W1975787075 @default.
- W1744006947 cites W1976785311 @default.
- W1744006947 cites W1980963048 @default.
- W1744006947 cites W1985029768 @default.
- W1744006947 cites W1986613820 @default.
- W1744006947 cites W1986903527 @default.
- W1744006947 cites W1990261439 @default.
- W1744006947 cites W1992598298 @default.
- W1744006947 cites W1993697079 @default.
- W1744006947 cites W1998767819 @default.
- W1744006947 cites W2009183417 @default.
- W1744006947 cites W2014610388 @default.
- W1744006947 cites W2014946489 @default.
- W1744006947 cites W2018368761 @default.
- W1744006947 cites W2030166934 @default.
- W1744006947 cites W2030367937 @default.
- W1744006947 cites W2042217178 @default.
- W1744006947 cites W2042907812 @default.
- W1744006947 cites W2047895710 @default.
- W1744006947 cites W2048960694 @default.
- W1744006947 cites W2049702532 @default.
- W1744006947 cites W2051227958 @default.
- W1744006947 cites W2055766265 @default.
- W1744006947 cites W2059998775 @default.
- W1744006947 cites W2071707768 @default.
- W1744006947 cites W2081094337 @default.
- W1744006947 cites W2082581434 @default.
- W1744006947 cites W2084578827 @default.
- W1744006947 cites W2087660989 @default.
- W1744006947 cites W2089858439 @default.
- W1744006947 cites W2093557716 @default.
- W1744006947 cites W2097655831 @default.
- W1744006947 cites W2101956922 @default.
- W1744006947 cites W2104488717 @default.
- W1744006947 cites W2105632406 @default.
- W1744006947 cites W2108104027 @default.
- W1744006947 cites W2108786888 @default.
- W1744006947 cites W2109791488 @default.
- W1744006947 cites W2112785261 @default.
- W1744006947 cites W2113047680 @default.
- W1744006947 cites W2114210474 @default.
- W1744006947 cites W2114557056 @default.
- W1744006947 cites W2115797469 @default.
- W1744006947 cites W2116402236 @default.
- W1744006947 cites W2126108346 @default.
- W1744006947 cites W2126663937 @default.
- W1744006947 cites W2128177327 @default.
- W1744006947 cites W2128340149 @default.
- W1744006947 cites W2131438518 @default.
- W1744006947 cites W2133763262 @default.
- W1744006947 cites W2135007926 @default.
- W1744006947 cites W2135314242 @default.
- W1744006947 cites W2135782550 @default.
- W1744006947 cites W2138664009 @default.
- W1744006947 cites W2139655181 @default.
- W1744006947 cites W2139933761 @default.
- W1744006947 cites W2141157874 @default.
- W1744006947 cites W2150536104 @default.
- W1744006947 cites W2157331935 @default.
- W1744006947 cites W2160467221 @default.
- W1744006947 cites W2161149887 @default.
- W1744006947 cites W2162198780 @default.
- W1744006947 cites W2162774116 @default.
- W1744006947 cites W2164079778 @default.
- W1744006947 cites W2168223870 @default.
- W1744006947 cites W2171230529 @default.
- W1744006947 cites W2172182613 @default.
- W1744006947 cites W2276249355 @default.
- W1744006947 cites W3023299375 @default.
- W1744006947 doi "https://doi.org/10.18632/oncotarget.424" @default.
- W1744006947 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3292888" @default.
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