Matches in SemOpenAlex for { <https://semopenalex.org/work/W174473103> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W174473103 abstract "Publisher Summary This chapter outlines chemical crosslinking studies of the interaction of calmodulin (CaM) with its receptors. Klevit and Vanaman developed techniques for specifically derivatizing Tyr 99 in calcium-binding site III or Tyr 138 in site IV (1), both in the C-domain of mammalian CaM. Benzophenone-labeled CaM, which was radio-iodinated at its sole tyrosine (125I-Bz-CaM), and native wheat germ CaM were found to be very similar to bovine CaM in their abilities to stimulate two mammalian enzyme systems—the Ca-ATPase of red blood cell membrane and the CaM-dependent kinase of cardiac Sarcoplasmic Reticulum (SR). The major product of the affinity labeling is a complex with a molecular mass of 40,000 daltons, which has been shown to be composed of CaM and phospholamban. Benzophenone-maleimide probe spans a distance of about 10 A from the sulfhydryl group of CaM to the photoactivatable carbonyl carbon of benzophenone, suggesting that Cys 27 is within 10 A of a binding site on phospholamban. Thus, this derivative will be a useful tool for CaM structure-function studies and studies defining CaM interactions with its receptors." @default.
- W174473103 created "2016-06-24" @default.
- W174473103 creator A5018636488 @default.
- W174473103 creator A5065404380 @default.
- W174473103 creator A5076012815 @default.
- W174473103 date "1987-01-01" @default.
- W174473103 modified "2023-10-16" @default.
- W174473103 title "A NOVEL CALMODULIN DERIVATIVE: STUDIES WITH CARDIAC SARCOPLASMIC RETICULUM" @default.
- W174473103 cites W1499736606 @default.
- W174473103 cites W1499775870 @default.
- W174473103 cites W1512695398 @default.
- W174473103 cites W1558794683 @default.
- W174473103 cites W1862634094 @default.
- W174473103 cites W2301973893 @default.
- W174473103 doi "https://doi.org/10.1016/b978-0-12-521040-9.50020-6" @default.
- W174473103 hasPublicationYear "1987" @default.
- W174473103 type Work @default.
- W174473103 sameAs 174473103 @default.
- W174473103 citedByCount "0" @default.
- W174473103 crossrefType "book-chapter" @default.
- W174473103 hasAuthorship W174473103A5018636488 @default.
- W174473103 hasAuthorship W174473103A5065404380 @default.
- W174473103 hasAuthorship W174473103A5076012815 @default.
- W174473103 hasConcept C107824862 @default.
- W174473103 hasConcept C12554922 @default.
- W174473103 hasConcept C158617107 @default.
- W174473103 hasConcept C170493617 @default.
- W174473103 hasConcept C17137333 @default.
- W174473103 hasConcept C181199279 @default.
- W174473103 hasConcept C185592680 @default.
- W174473103 hasConcept C2778279444 @default.
- W174473103 hasConcept C29688787 @default.
- W174473103 hasConcept C55493867 @default.
- W174473103 hasConcept C71240020 @default.
- W174473103 hasConcept C75473681 @default.
- W174473103 hasConcept C86803240 @default.
- W174473103 hasConceptScore W174473103C107824862 @default.
- W174473103 hasConceptScore W174473103C12554922 @default.
- W174473103 hasConceptScore W174473103C158617107 @default.
- W174473103 hasConceptScore W174473103C170493617 @default.
- W174473103 hasConceptScore W174473103C17137333 @default.
- W174473103 hasConceptScore W174473103C181199279 @default.
- W174473103 hasConceptScore W174473103C185592680 @default.
- W174473103 hasConceptScore W174473103C2778279444 @default.
- W174473103 hasConceptScore W174473103C29688787 @default.
- W174473103 hasConceptScore W174473103C55493867 @default.
- W174473103 hasConceptScore W174473103C71240020 @default.
- W174473103 hasConceptScore W174473103C75473681 @default.
- W174473103 hasConceptScore W174473103C86803240 @default.
- W174473103 hasLocation W1744731031 @default.
- W174473103 hasOpenAccess W174473103 @default.
- W174473103 hasPrimaryLocation W1744731031 @default.
- W174473103 hasRelatedWork W1576403707 @default.
- W174473103 hasRelatedWork W1583235731 @default.
- W174473103 hasRelatedWork W1591210132 @default.
- W174473103 hasRelatedWork W1976674188 @default.
- W174473103 hasRelatedWork W1982397583 @default.
- W174473103 hasRelatedWork W1991567031 @default.
- W174473103 hasRelatedWork W2006164844 @default.
- W174473103 hasRelatedWork W2010237285 @default.
- W174473103 hasRelatedWork W2012088552 @default.
- W174473103 hasRelatedWork W2027270341 @default.
- W174473103 hasRelatedWork W2043853386 @default.
- W174473103 hasRelatedWork W2067686089 @default.
- W174473103 hasRelatedWork W2070590783 @default.
- W174473103 hasRelatedWork W2111054934 @default.
- W174473103 hasRelatedWork W2142148418 @default.
- W174473103 hasRelatedWork W2145982644 @default.
- W174473103 hasRelatedWork W2167135214 @default.
- W174473103 hasRelatedWork W2231651107 @default.
- W174473103 hasRelatedWork W1585811005 @default.
- W174473103 hasRelatedWork W2031011317 @default.
- W174473103 isParatext "false" @default.
- W174473103 isRetracted "false" @default.
- W174473103 magId "174473103" @default.
- W174473103 workType "book-chapter" @default.