FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W174753030> ?p ?o ?g. }

• W174753030 endingPage "6" @default.
• W174753030 startingPage "83" @default.
• W174753030 abstract "Galactomannan (GM) is a major aspergilli cell-wall constituent released into circulation during the early stage of invasive disease, and can be detected. Many studies suggest that serum galactomannan assay has an excellent sensitivity and specificity for the early diagnosis of adult invasive aspergillosis (IA). However, there have been few studies on serum galactomannan assay in pediatric patients. Therefore, we evaluate the value of serum galactomannan assay in the diagnosis of pediatric invasive pulmonary aspergillosis in this study.Blood samples were obtained from 88 children, of whom 14 had definitive or possible invasive pulmonary aspergillosis (IPA), 16 had other invasive pulmonary fungal infection and 58 had pulmonary non-fungal infection. Of the 58 patients, 23 had bacterial pneumonia, 20 had mycoplasma pneumonia and 15 had pulmonary tuberculosis. A double-direct sandwich ELISA was employed to detect GM optical density index (ODI) in the serum sample. GM ODI were observed before and after treatment in six children with IPA. Measurement data followed the Gaussian distribution were expressed as x(-) +/- s; differences among groups were tested using a single factor analysis of variance. If the s>1/3 x(-), measurement data were expressed as M [minimum, maximum], and the differences among groups were tested by a rank sum test. P < 0.05 was considered to be statistically significant.The serum GM ODI in IPA group [1.03 (0.16 - 3.73)] was significantly higher than that in the other invasive pulmonary fungal infection group [0.30 (0.04 - 1.28)] and pulmonary non-fungal infection group [0.24 (0.08 - 0.69)] (P < 0.05). If the cut-off GM ODI was set at 0.5, the sensitivity and specificity of the assay for IPA were 71.4% and 91.9% respectively. The accuracy rate for IPA was 88.6%. If the cut-off GM ODI was set at 0.8, the sensitivity, specificity and accuracy rate for IPA were 64.2%, 98.6% and 93.2% respectively. Of 6 children whose GM were observed serially, GM ODI declined consistently with the clinical remission in 3 children. GM ODI raised in 2 children corresponding to clinical exacerbation. Whereas GM ODI elevated paradoxically regardless of clinical remission in the remaining one patient.Serum GM detection was an effective method for the diagnosis of pediatric IPA." @default.
• W174753030 created "2016-06-24" @default.
• W174753030 creator A5019475169 @default.
• W174753030 creator A5021636467 @default.
• W174753030 creator A5047778742 @default.
• W174753030 date "2009-02-01" @default.
• W174753030 modified "2023-10-16" @default.
• W174753030 title "[Value of serum galactomannan assay in the diagnosis of pediatric invasive pulmonary aspergillosis]." @default.
• W174753030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19573449" @default.
• W174753030 hasPublicationYear "2009" @default.
• W174753030 type Work @default.
• W174753030 sameAs 174753030 @default.
• W174753030 citedByCount "2" @default.
• W174753030 countsByYear W1747530302017 @default.
• W174753030 crossrefType "journal-article" @default.
• W174753030 hasAuthorship W174753030A5019475169 @default.
• W174753030 hasAuthorship W174753030A5021636467 @default.
• W174753030 hasAuthorship W174753030A5047778742 @default.
• W174753030 hasConcept C126322002 @default.
• W174753030 hasConcept C203014093 @default.
• W174753030 hasConcept C2776391196 @default.
• W174753030 hasConcept C2777914695 @default.
• W174753030 hasConcept C2779175654 @default.
• W174753030 hasConcept C2779215961 @default.
• W174753030 hasConcept C2779706735 @default.
• W174753030 hasConcept C2780782397 @default.
• W174753030 hasConcept C71924100 @default.
• W174753030 hasConcept C86803240 @default.
• W174753030 hasConcept C89423630 @default.
• W174753030 hasConcept C90924648 @default.
• W174753030 hasConceptScore W174753030C126322002 @default.
• W174753030 hasConceptScore W174753030C203014093 @default.
• W174753030 hasConceptScore W174753030C2776391196 @default.
• W174753030 hasConceptScore W174753030C2777914695 @default.
• W174753030 hasConceptScore W174753030C2779175654 @default.
• W174753030 hasConceptScore W174753030C2779215961 @default.
• W174753030 hasConceptScore W174753030C2779706735 @default.
• W174753030 hasConceptScore W174753030C2780782397 @default.
• W174753030 hasConceptScore W174753030C71924100 @default.
• W174753030 hasConceptScore W174753030C86803240 @default.
• W174753030 hasConceptScore W174753030C89423630 @default.
• W174753030 hasConceptScore W174753030C90924648 @default.
• W174753030 hasIssue "2" @default.
• W174753030 hasLocation W1747530301 @default.
• W174753030 hasOpenAccess W174753030 @default.
• W174753030 hasPrimaryLocation W1747530301 @default.
• W174753030 hasRelatedWork W174753030 @default.
• W174753030 hasRelatedWork W2065419377 @default.
• W174753030 hasRelatedWork W2105583792 @default.
• W174753030 hasRelatedWork W2171659145 @default.
• W174753030 hasRelatedWork W2301477544 @default.
• W174753030 hasRelatedWork W2394837408 @default.
• W174753030 hasRelatedWork W2756894274 @default.
• W174753030 hasRelatedWork W2901197011 @default.
• W174753030 hasRelatedWork W3088068397 @default.
• W174753030 hasRelatedWork W4220807851 @default.
• W174753030 hasVolume "47" @default.
• W174753030 isParatext "false" @default.
• W174753030 isRetracted "false" @default.
• W174753030 magId "174753030" @default.
• W174753030 workType "article" @default.