Matches in SemOpenAlex for { <https://semopenalex.org/work/W1749330131> ?p ?o ?g. }
- W1749330131 endingPage "9" @default.
- W1749330131 startingPage "1" @default.
- W1749330131 abstract "Introduction . The aim of the present study was to investigate whether a 12-hour exposure in a normobaric hypoxic chamber would induce changes in the hemostatic system and a procoagulant state in volunteers suffering from acute mountain sickness (AMS) and healthy controls. Materials and Methods . 37 healthy participants were passively exposed to 12.6% FiO 2 (simulated altitude hypoxia of 4,500 m). AMS development was investigated by the Lake Louise Score (LLS). Prothrombin time, activated partial thromboplastin time, fibrinogen, and platelet count were measured and specific methods (i.e., thromboelastometry and a thrombin generation test) were used. Results . AMS prevalence was 62.2% (LLS cut off of 3). For the whole group, paired sample t -tests showed significant increase in the maximal concentration of generated thrombin. ROTEM measurements revealed a significant shortening of coagulation time and an increase of maximal clot firmness (InTEM test). A significant increase in maximum clot firmness could be shown (FibTEM test). Conclusions . All significant changes in coagulation parameters after exposure remained within normal reference ranges. No differences with regard to measured parameters of the hemostatic system between AMS-positive and -negative subjects were observed. Therefore, the hypothesis of the acute activation of coagulation by hypoxia can be rejected." @default.
- W1749330131 created "2016-06-24" @default.
- W1749330131 creator A5005071872 @default.
- W1749330131 creator A5007480882 @default.
- W1749330131 creator A5030596866 @default.
- W1749330131 creator A5039724225 @default.
- W1749330131 creator A5040926639 @default.
- W1749330131 creator A5056971117 @default.
- W1749330131 creator A5058309613 @default.
- W1749330131 creator A5063951971 @default.
- W1749330131 date "2015-01-01" @default.
- W1749330131 modified "2023-09-25" @default.
- W1749330131 title "Influence of Acute Normobaric Hypoxia on Hemostasis in Volunteers with and without Acute Mountain Sickness" @default.
- W1749330131 cites W141479429 @default.
- W1749330131 cites W1521360630 @default.
- W1749330131 cites W165084168 @default.
- W1749330131 cites W1672725959 @default.
- W1749330131 cites W1913915712 @default.
- W1749330131 cites W1968625808 @default.
- W1749330131 cites W1970289843 @default.
- W1749330131 cites W1974877562 @default.
- W1749330131 cites W1975182806 @default.
- W1749330131 cites W1978039741 @default.
- W1749330131 cites W1987677883 @default.
- W1749330131 cites W1988375929 @default.
- W1749330131 cites W1990549548 @default.
- W1749330131 cites W1991912892 @default.
- W1749330131 cites W2001515209 @default.
- W1749330131 cites W2003768002 @default.
- W1749330131 cites W2007364530 @default.
- W1749330131 cites W2019570438 @default.
- W1749330131 cites W2019746767 @default.
- W1749330131 cites W2025456672 @default.
- W1749330131 cites W2032721285 @default.
- W1749330131 cites W2040254529 @default.
- W1749330131 cites W2041441905 @default.
- W1749330131 cites W2047089875 @default.
- W1749330131 cites W2048784133 @default.
- W1749330131 cites W2066548422 @default.
- W1749330131 cites W2066746471 @default.
- W1749330131 cites W2066813153 @default.
- W1749330131 cites W2068462444 @default.
- W1749330131 cites W2076141362 @default.
- W1749330131 cites W2076196046 @default.
- W1749330131 cites W2087616265 @default.
- W1749330131 cites W2089866557 @default.
- W1749330131 cites W2095982855 @default.
- W1749330131 cites W2097016664 @default.
- W1749330131 cites W2099623343 @default.
- W1749330131 cites W2105716028 @default.
- W1749330131 cites W2119125490 @default.
- W1749330131 cites W2140245157 @default.
- W1749330131 cites W2142129510 @default.
- W1749330131 cites W2149155137 @default.
- W1749330131 cites W2150903719 @default.
- W1749330131 cites W2163165335 @default.
- W1749330131 cites W2167516774 @default.
- W1749330131 cites W2169167592 @default.
- W1749330131 cites W2170465499 @default.
- W1749330131 cites W2173333031 @default.
- W1749330131 cites W2332276621 @default.
- W1749330131 cites W2339851248 @default.
- W1749330131 cites W2365854328 @default.
- W1749330131 cites W2394818437 @default.
- W1749330131 cites W2417102934 @default.
- W1749330131 cites W2748435152 @default.
- W1749330131 cites W2793538523 @default.
- W1749330131 cites W4232642121 @default.
- W1749330131 cites W4238149923 @default.
- W1749330131 cites W4243079255 @default.
- W1749330131 cites W4250975534 @default.
- W1749330131 doi "https://doi.org/10.1155/2015/593938" @default.
- W1749330131 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4586904" @default.
- W1749330131 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26451374" @default.
- W1749330131 hasPublicationYear "2015" @default.
- W1749330131 type Work @default.
- W1749330131 sameAs 1749330131 @default.
- W1749330131 citedByCount "13" @default.
- W1749330131 countsByYear W17493301312017 @default.
- W1749330131 countsByYear W17493301312019 @default.
- W1749330131 countsByYear W17493301312020 @default.
- W1749330131 countsByYear W17493301312022 @default.
- W1749330131 countsByYear W17493301312023 @default.
- W1749330131 crossrefType "journal-article" @default.
- W1749330131 hasAuthorship W1749330131A5005071872 @default.
- W1749330131 hasAuthorship W1749330131A5007480882 @default.
- W1749330131 hasAuthorship W1749330131A5030596866 @default.
- W1749330131 hasAuthorship W1749330131A5039724225 @default.
- W1749330131 hasAuthorship W1749330131A5040926639 @default.
- W1749330131 hasAuthorship W1749330131A5056971117 @default.
- W1749330131 hasAuthorship W1749330131A5058309613 @default.
- W1749330131 hasAuthorship W1749330131A5063951971 @default.
- W1749330131 hasBestOaLocation W17493301311 @default.
- W1749330131 hasConcept C126322002 @default.
- W1749330131 hasConcept C16124881 @default.
- W1749330131 hasConcept C178790620 @default.
- W1749330131 hasConcept C185592680 @default.
- W1749330131 hasConcept C26809991 @default.