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• W1749640215 abstract "Although Candida albicans (CA) is the most common cause of Candida bloodstream Infections (BSIs), recent studies have observed an Increasing percentage of candidaemias caused by non-albicans Candida species (NAC). In the present study, we attempted to identify the predictors of candidaemia due to NAC compared to CA. We analyzed data from an active population-based surveillance in Barcelona (Spain) from January 2002 to December 2003. Factors associated with NAC fungaemia were determined by multivariate analysis. A total of 339 episodes of Candida BSI, in 336 patients (median age 63 years, interquartile range: 41–72 years), were included. CA was the most commonly isolated (52%), followed by Candida parapsilosis (23%), Candida tropicalis (10%), Candida glabrata (8.6%), Candida krusei (3.4%) and other NAC spp. (3%). Overall, 48% of cases were due to NAC spp. Multivariate logistic regression analysis identified factors associated with a risk of BSI due to NAC spp.: having received a haematologic transplant (OR 10.8; 95% CI 1.31–90.01; p 0.027), previous fluconazole exposure (OR 4.47; 95% CI 2.12–9.43; p <0.001) and neonatal age (OR 4.42; 95% CI 1.63–12.04; p 0.004). Conversely, previous CA colonization (OR 0.33; 95% CI 0.19–0.57; p 0.001) and previous antibiotic use (OR 0.42; 95% CI 0.21–0.85; p 0.017) were associated with CA fungaemia compared to NAC. In conclusion, NAC candidaemia comprised 48% of cases in our series. Predictors of NAC include having received a haematologic transplant, neonatal age and previous fluconazole use." @default.
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• W1749640215 date "2010-11-01" @default.
• W1749640215 modified "2023-10-09" @default.
• W1749640215 title "Predictors of candidaemia caused by non-albicans Candida species: results of a population-based surveillance in Barcelona, Spain" @default.
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• W1749640215 doi "https://doi.org/10.1111/j.1469-0691.2010.03208.x" @default.
• W1749640215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20219079" @default.
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