FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1749777616> ?p ?o ?g. }

• W1749777616 endingPage "3030" @default.
• W1749777616 startingPage "3025" @default.
• W1749777616 abstract "Penicillin-binding protein 2 (PBP2), target of the beta-lactam mecillinam, is required for rod morphology and cell wall elongation in Escherichia coli. A new temperature-sensitive PBP2 allele and an in vitro-constructed insertion deletion allele were shown to be lethal in wild-type strains, establishing that the activity of this protein is essential. Mutations in the lov or cya genes, conferring mecillinam resistance, compensated for the deleterious effect of the absence of PBP2. The resulting double mutants grew as spheres. In a cya mutant lacking PBP2, the restoration of a Cya+ phenotype by addition of cyclic AMP caused lethality and a block in cell division. These results show that in wild-type cells, PBP2 is essential for growth and division." @default.
• W1749777616 created "2016-06-24" @default.
• W1749777616 creator A5009525454 @default.
• W1749777616 creator A5015534186 @default.
• W1749777616 creator A5020554149 @default.
• W1749777616 creator A5070536306 @default.
• W1749777616 creator A5074442125 @default.
• W1749777616 creator A5088568559 @default.
• W1749777616 date "1989-06-01" @default.
• W1749777616 modified "2023-09-23" @default.
• W1749777616 title "Penicillin-binding protein 2 is essential in wild-type Escherichia coli but not in lov or cya mutants" @default.
• W1749777616 cites W1499223085 @default.
• W1749777616 cites W1511274937 @default.
• W1749777616 cites W1513442717 @default.
• W1749777616 cites W1513888946 @default.
• W1749777616 cites W1519455679 @default.
• W1749777616 cites W1532029656 @default.
• W1749777616 cites W1532541041 @default.
• W1749777616 cites W1547904721 @default.
• W1749777616 cites W1580778748 @default.
• W1749777616 cites W1590630614 @default.
• W1749777616 cites W1602369257 @default.
• W1749777616 cites W1658141389 @default.
• W1749777616 cites W1761797681 @default.
• W1749777616 cites W18385036 @default.
• W1749777616 cites W1859453763 @default.
• W1749777616 cites W1931305867 @default.
• W1749777616 cites W1964956614 @default.
• W1749777616 cites W1973670295 @default.
• W1749777616 cites W1989423690 @default.
• W1749777616 cites W1992006277 @default.
• W1749777616 cites W2002984572 @default.
• W1749777616 cites W2015117724 @default.
• W1749777616 cites W2026921519 @default.
• W1749777616 cites W2043268620 @default.
• W1749777616 cites W2060561490 @default.
• W1749777616 cites W2092747903 @default.
• W1749777616 cites W2111555302 @default.
• W1749777616 cites W2125582289 @default.
• W1749777616 cites W2132446085 @default.
• W1749777616 cites W2132476073 @default.
• W1749777616 cites W2136485465 @default.
• W1749777616 cites W2141653906 @default.
• W1749777616 cites W2146558355 @default.
• W1749777616 cites W2155467771 @default.
• W1749777616 cites W2163279482 @default.
• W1749777616 cites W2916217134 @default.
• W1749777616 cites W3183899877 @default.
• W1749777616 doi "https://doi.org/10.1128/jb.171.6.3025-3030.1989" @default.
• W1749777616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/210010" @default.
• W1749777616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2656638" @default.
• W1749777616 hasPublicationYear "1989" @default.
• W1749777616 type Work @default.
• W1749777616 sameAs 1749777616 @default.
• W1749777616 citedByCount "71" @default.
• W1749777616 countsByYear W17497776162013 @default.
• W1749777616 countsByYear W17497776162014 @default.
• W1749777616 countsByYear W17497776162015 @default.
• W1749777616 countsByYear W17497776162016 @default.
• W1749777616 countsByYear W17497776162017 @default.
• W1749777616 countsByYear W17497776162018 @default.
• W1749777616 countsByYear W17497776162019 @default.
• W1749777616 countsByYear W17497776162022 @default.
• W1749777616 crossrefType "journal-article" @default.
• W1749777616 hasAuthorship W1749777616A5009525454 @default.
• W1749777616 hasAuthorship W1749777616A5015534186 @default.
• W1749777616 hasAuthorship W1749777616A5020554149 @default.
• W1749777616 hasAuthorship W1749777616A5070536306 @default.
• W1749777616 hasAuthorship W1749777616A5074442125 @default.
• W1749777616 hasAuthorship W1749777616A5088568559 @default.
• W1749777616 hasBestOaLocation W17497776162 @default.
• W1749777616 hasConcept C104317684 @default.
• W1749777616 hasConcept C143065580 @default.
• W1749777616 hasConcept C1491633281 @default.
• W1749777616 hasConcept C207583985 @default.
• W1749777616 hasConcept C2776653525 @default.
• W1749777616 hasConcept C2777894859 @default.
• W1749777616 hasConcept C2778910516 @default.
• W1749777616 hasConcept C501734568 @default.
• W1749777616 hasConcept C54355233 @default.
• W1749777616 hasConcept C547475151 @default.
• W1749777616 hasConcept C85813293 @default.
• W1749777616 hasConcept C86803240 @default.
• W1749777616 hasConcept C89423630 @default.
• W1749777616 hasConceptScore W1749777616C104317684 @default.
• W1749777616 hasConceptScore W1749777616C143065580 @default.
• W1749777616 hasConceptScore W1749777616C1491633281 @default.
• W1749777616 hasConceptScore W1749777616C207583985 @default.
• W1749777616 hasConceptScore W1749777616C2776653525 @default.
• W1749777616 hasConceptScore W1749777616C2777894859 @default.
• W1749777616 hasConceptScore W1749777616C2778910516 @default.
• W1749777616 hasConceptScore W1749777616C501734568 @default.
• W1749777616 hasConceptScore W1749777616C54355233 @default.
• W1749777616 hasConceptScore W1749777616C547475151 @default.
• W1749777616 hasConceptScore W1749777616C85813293 @default.
• W1749777616 hasConceptScore W1749777616C86803240 @default.
• W1749777616 hasConceptScore W1749777616C89423630 @default.
• W1749777616 hasIssue "6" @default.

• next