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- W174999955 abstract "nm thick) were collected on copper grids, stainedwith uranyl acetate and lead citrate, and observedwith a JEOL 1200 EX II electron microscope.Morphological examination of the control midgut,fed with blood of a healthy donor revealed a fullydeveloped PM by 16 h (Fig. 1). It appears at the lightmicroscope level as a light brownish layer betweenthe interstitial epithelium and the alimentary bolus.The PM structure was recognised as an amorphousand laminated structure segregating the blood meal.The PM enclosed and surrounded the entire bloodmeal just above the epithelium. The PM increasedits thickness at 20 h and decreased at 24 h, in themidgut obtained from Anopheles (Fig. 1), when theinsects were fed with the blood of a healthy donor.The natural colour (dark) can be attributed to thepresence of haeme bound to the matrix and to haemeprecipitates clearly visible between the erythrocytesand the PM after the blood meal. PM formation wasloosed in midgut of Anopheles fed with blood of ahealthy donor added with plasma of malaria patientscontaining 0.68 and 0.95 mU/ml of Chit. Also thePM in the midgut of Anopheles fed with the blood ofa healthy donor added with plasma of Gaucher dis-High levels of plasma chitotriosidase (Chit) repre-sents a marker of macrophage activation in humanmalaria infection" @default.
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- W174999955 date "2006-09-01" @default.
- W174999955 modified "2023-09-23" @default.
- W174999955 title "Human chitotriosidase helps Plasmodium falciparum in the Anopheles midgut." @default.
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