Matches in SemOpenAlex for { <https://semopenalex.org/work/W1750260739> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1750260739 endingPage "7001" @default.
- W1750260739 startingPage "6997" @default.
- W1750260739 abstract "We evaluated the virulence of replication-competent NA-negative (no functional neuraminidase) avian influenza viruses in chicken of different ages. Interestingly, the virulence of a previously described NA-negative H5-virus (Kalthoff et al., J Virol 2013;87:13556) is very much age-dependent. Day-old-chicks succumb to a systemic infection, while chicken one week of age do not show any clinical signs at all. Therefore, the day-old-chick organism is most likely not able to restrict replication of the virus as older chicken do. In addition to virulence dependency on host age, the exchange of the H5 HA by an H7 HA for an H7NA-deleted HA reassortant remarkably led to a highly pathogenic phenotype even in adult chicken. This provides evidence, that the virulence of the H7-subtype is less dependent on the NA-protein than that of the H5-virus. These striking observations suggest that the HA/NA interplay might be governed by other mechanisms in HPAIV with the different serotypes H5 or H7." @default.
- W1750260739 created "2016-06-24" @default.
- W1750260739 creator A5001905405 @default.
- W1750260739 creator A5015433353 @default.
- W1750260739 creator A5017296714 @default.
- W1750260739 creator A5036973907 @default.
- W1750260739 creator A5077161569 @default.
- W1750260739 date "2015-12-01" @default.
- W1750260739 modified "2023-09-23" @default.
- W1750260739 title "Pathogenicity evaluation of neuraminidase-negative H5 and H7 viruses in day-old chicks and adult chicken" @default.
- W1750260739 cites W1969695577 @default.
- W1750260739 cites W1989567051 @default.
- W1750260739 cites W2002041392 @default.
- W1750260739 cites W2031403580 @default.
- W1750260739 cites W2050306167 @default.
- W1750260739 cites W2077458179 @default.
- W1750260739 cites W2079241366 @default.
- W1750260739 cites W2081000303 @default.
- W1750260739 cites W2083419156 @default.
- W1750260739 cites W2091527885 @default.
- W1750260739 cites W2110998010 @default.
- W1750260739 cites W2130947840 @default.
- W1750260739 cites W2135764235 @default.
- W1750260739 doi "https://doi.org/10.1016/j.vaccine.2015.09.106" @default.
- W1750260739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26469725" @default.
- W1750260739 hasPublicationYear "2015" @default.
- W1750260739 type Work @default.
- W1750260739 sameAs 1750260739 @default.
- W1750260739 citedByCount "3" @default.
- W1750260739 countsByYear W17502607392019 @default.
- W1750260739 countsByYear W17502607392023 @default.
- W1750260739 crossrefType "journal-article" @default.
- W1750260739 hasAuthorship W1750260739A5001905405 @default.
- W1750260739 hasAuthorship W1750260739A5015433353 @default.
- W1750260739 hasAuthorship W1750260739A5017296714 @default.
- W1750260739 hasAuthorship W1750260739A5036973907 @default.
- W1750260739 hasAuthorship W1750260739A5077161569 @default.
- W1750260739 hasConcept C10389963 @default.
- W1750260739 hasConcept C104317684 @default.
- W1750260739 hasConcept C126831891 @default.
- W1750260739 hasConcept C127716648 @default.
- W1750260739 hasConcept C134164806 @default.
- W1750260739 hasConcept C140704245 @default.
- W1750260739 hasConcept C159047783 @default.
- W1750260739 hasConcept C2522874641 @default.
- W1750260739 hasConcept C519248777 @default.
- W1750260739 hasConcept C54355233 @default.
- W1750260739 hasConcept C60987743 @default.
- W1750260739 hasConcept C86803240 @default.
- W1750260739 hasConcept C89423630 @default.
- W1750260739 hasConceptScore W1750260739C10389963 @default.
- W1750260739 hasConceptScore W1750260739C104317684 @default.
- W1750260739 hasConceptScore W1750260739C126831891 @default.
- W1750260739 hasConceptScore W1750260739C127716648 @default.
- W1750260739 hasConceptScore W1750260739C134164806 @default.
- W1750260739 hasConceptScore W1750260739C140704245 @default.
- W1750260739 hasConceptScore W1750260739C159047783 @default.
- W1750260739 hasConceptScore W1750260739C2522874641 @default.
- W1750260739 hasConceptScore W1750260739C519248777 @default.
- W1750260739 hasConceptScore W1750260739C54355233 @default.
- W1750260739 hasConceptScore W1750260739C60987743 @default.
- W1750260739 hasConceptScore W1750260739C86803240 @default.
- W1750260739 hasConceptScore W1750260739C89423630 @default.
- W1750260739 hasIssue "49" @default.
- W1750260739 hasLocation W17502607391 @default.
- W1750260739 hasLocation W17502607392 @default.
- W1750260739 hasOpenAccess W1750260739 @default.
- W1750260739 hasPrimaryLocation W17502607391 @default.
- W1750260739 hasRelatedWork W1977378082 @default.
- W1750260739 hasRelatedWork W2024956434 @default.
- W1750260739 hasRelatedWork W2035643332 @default.
- W1750260739 hasRelatedWork W2103093438 @default.
- W1750260739 hasRelatedWork W2170463474 @default.
- W1750260739 hasRelatedWork W2193331226 @default.
- W1750260739 hasRelatedWork W2613621187 @default.
- W1750260739 hasRelatedWork W2992274268 @default.
- W1750260739 hasRelatedWork W2998426862 @default.
- W1750260739 hasRelatedWork W3187641169 @default.
- W1750260739 hasVolume "33" @default.
- W1750260739 isParatext "false" @default.
- W1750260739 isRetracted "false" @default.
- W1750260739 magId "1750260739" @default.
- W1750260739 workType "article" @default.