Matches in SemOpenAlex for { <https://semopenalex.org/work/W175058339> ?p ?o ?g. }
- W175058339 endingPage "768" @default.
- W175058339 startingPage "763" @default.
- W175058339 abstract "The flux rates of plasma glucose and alanine were studied isotopically (6-3H-glucose and U-14C-alanine simultaneously) in resting chronically diabetic dogs during short-term treatment with an artificial B cell where the insulin was infused into a peripheral vein. Despite perfect blood glucose control and normal glucose flux rates, the concentration and rates of appearance and disappearance of alanine were significantly elevated in the diabetic animals before, during and after an exogenous glucose load. The incorporation of the carbon moiety of alanine into circulating glucose was also increased, but diminished to a near-normal extent when exogenous glucose was given. The plasma clearance rates for alanine in the diabetic dogs were normal throughout the study. It is concluded that normal blood glucose control in diabetes does not necessarily mean normalization of the entire metabolic network. On the basis of peripheral hyperinsulinaemia alanine formation from glucose and branched chain amino acids is elevated in muscle. This may explain increased flux of alanine despite normal blood glucose control." @default.
- W175058339 created "2016-06-24" @default.
- W175058339 creator A5002749079 @default.
- W175058339 creator A5013173339 @default.
- W175058339 creator A5041229885 @default.
- W175058339 creator A5083479320 @default.
- W175058339 date "1985-10-01" @default.
- W175058339 modified "2023-09-30" @default.
- W175058339 title "Alterations in alanine metabolism in diabetic dogs during short-term treatment with an artificial B cell" @default.
- W175058339 cites W1483387535 @default.
- W175058339 cites W1502242927 @default.
- W175058339 cites W1603212466 @default.
- W175058339 cites W1974348798 @default.
- W175058339 cites W1977420916 @default.
- W175058339 cites W1982313710 @default.
- W175058339 cites W1998718966 @default.
- W175058339 cites W2004009337 @default.
- W175058339 cites W2006779085 @default.
- W175058339 cites W2019372846 @default.
- W175058339 cites W2021246671 @default.
- W175058339 cites W2026912546 @default.
- W175058339 cites W2036391301 @default.
- W175058339 cites W2045908033 @default.
- W175058339 cites W2051941969 @default.
- W175058339 cites W2059760953 @default.
- W175058339 cites W2060219639 @default.
- W175058339 cites W2070290236 @default.
- W175058339 cites W2093889602 @default.
- W175058339 cites W2102941122 @default.
- W175058339 cites W2107037674 @default.
- W175058339 cites W2116815537 @default.
- W175058339 cites W2124232607 @default.
- W175058339 cites W2136631681 @default.
- W175058339 cites W2153637373 @default.
- W175058339 cites W2178774593 @default.
- W175058339 cites W2181988588 @default.
- W175058339 cites W2205678622 @default.
- W175058339 cites W2263909751 @default.
- W175058339 cites W2395677718 @default.
- W175058339 cites W2412258083 @default.
- W175058339 cites W2412620640 @default.
- W175058339 cites W2462102230 @default.
- W175058339 cites W2464308311 @default.
- W175058339 cites W334797427 @default.
- W175058339 cites W2405142890 @default.
- W175058339 doi "https://doi.org/10.1007/bf00265025" @default.
- W175058339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4065451" @default.
- W175058339 hasPublicationYear "1985" @default.
- W175058339 type Work @default.
- W175058339 sameAs 175058339 @default.
- W175058339 citedByCount "3" @default.
- W175058339 crossrefType "journal-article" @default.
- W175058339 hasAuthorship W175058339A5002749079 @default.
- W175058339 hasAuthorship W175058339A5013173339 @default.
- W175058339 hasAuthorship W175058339A5041229885 @default.
- W175058339 hasAuthorship W175058339A5083479320 @default.
- W175058339 hasBestOaLocation W1750583391 @default.
- W175058339 hasConcept C126322002 @default.
- W175058339 hasConcept C134018914 @default.
- W175058339 hasConcept C17093226 @default.
- W175058339 hasConcept C185592680 @default.
- W175058339 hasConcept C2779306644 @default.
- W175058339 hasConcept C2779856020 @default.
- W175058339 hasConcept C515207424 @default.
- W175058339 hasConcept C55493867 @default.
- W175058339 hasConcept C555293320 @default.
- W175058339 hasConcept C62231903 @default.
- W175058339 hasConcept C71924100 @default.
- W175058339 hasConcept C86803240 @default.
- W175058339 hasConceptScore W175058339C126322002 @default.
- W175058339 hasConceptScore W175058339C134018914 @default.
- W175058339 hasConceptScore W175058339C17093226 @default.
- W175058339 hasConceptScore W175058339C185592680 @default.
- W175058339 hasConceptScore W175058339C2779306644 @default.
- W175058339 hasConceptScore W175058339C2779856020 @default.
- W175058339 hasConceptScore W175058339C515207424 @default.
- W175058339 hasConceptScore W175058339C55493867 @default.
- W175058339 hasConceptScore W175058339C555293320 @default.
- W175058339 hasConceptScore W175058339C62231903 @default.
- W175058339 hasConceptScore W175058339C71924100 @default.
- W175058339 hasConceptScore W175058339C86803240 @default.
- W175058339 hasIssue "10" @default.
- W175058339 hasLocation W1750583391 @default.
- W175058339 hasLocation W1750583392 @default.
- W175058339 hasOpenAccess W175058339 @default.
- W175058339 hasPrimaryLocation W1750583391 @default.
- W175058339 hasRelatedWork W1983912401 @default.
- W175058339 hasRelatedWork W1986933516 @default.
- W175058339 hasRelatedWork W2023313620 @default.
- W175058339 hasRelatedWork W2054690921 @default.
- W175058339 hasRelatedWork W2080086386 @default.
- W175058339 hasRelatedWork W2087100186 @default.
- W175058339 hasRelatedWork W2096420073 @default.
- W175058339 hasRelatedWork W2150247094 @default.
- W175058339 hasRelatedWork W2150355182 @default.
- W175058339 hasRelatedWork W2169445449 @default.
- W175058339 hasVolume "28" @default.
- W175058339 isParatext "false" @default.