Matches in SemOpenAlex for { <https://semopenalex.org/work/W175064070> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W175064070 endingPage "H2135" @default.
- W175064070 startingPage "H2131" @default.
- W175064070 abstract "Isovolemic hemodilution and subsequent anemia increase cerebral blood flow (CBF). We hypothesized that pial microvascular pressure also increases with hemodilution and that arteriolar diameter varies concurrently as a myogenic autoregulatory response. First- and second-order arterioles (31-92 microns, n = 29) and large venules (65-215 microns, n = 17) were studied in thiopental-anesthetized rats. Microvascular pressure was determined using the servo-null technique, and vessel diameters were obtained directly from a video monitoring system. We measured the increase in CBF (radiolabeled microspheres) that accompanies hemodilution in a separate group of animals (n = 20). Hematocrit was reduced to 16-36% with homologous plasma (hemodilution group, n = 13) or held constant with homologous whole blood (control group, n = 4). In control animals, arteriolar and venular diameter varied +/- 1-2 microns from baseline values, and microvascular pressure remained unchanged from baseline. In the hemodilution group, CBF increased, but there was no systematic pial vasodilation. Furthermore, intraluminal pressure did not increase in pial microvessels, suggesting that proximal vasodilation was negligible even at the lowest hematocrit studied. Vascular resistance fell proportionately in both large vessel and microvascular segments. We conclude that experimental anemia does not produce alterations in microvascular pressure in rats, and the hyperemia accompanying hemodilution is largely viscosity mediated." @default.
- W175064070 created "2016-06-24" @default.
- W175064070 creator A5005438739 @default.
- W175064070 creator A5013192404 @default.
- W175064070 creator A5059485117 @default.
- W175064070 creator A5060319184 @default.
- W175064070 date "1993-06-01" @default.
- W175064070 modified "2023-09-29" @default.
- W175064070 title "Pial microvascular hemodynamics in anemia" @default.
- W175064070 doi "https://doi.org/10.1152/ajpheart.1993.264.6.h2131" @default.
- W175064070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8322943" @default.
- W175064070 hasPublicationYear "1993" @default.
- W175064070 type Work @default.
- W175064070 sameAs 175064070 @default.
- W175064070 citedByCount "14" @default.
- W175064070 countsByYear W1750640702015 @default.
- W175064070 countsByYear W1750640702016 @default.
- W175064070 countsByYear W1750640702017 @default.
- W175064070 countsByYear W1750640702021 @default.
- W175064070 crossrefType "journal-article" @default.
- W175064070 hasAuthorship W175064070A5005438739 @default.
- W175064070 hasAuthorship W175064070A5013192404 @default.
- W175064070 hasAuthorship W175064070A5059485117 @default.
- W175064070 hasAuthorship W175064070A5060319184 @default.
- W175064070 hasConcept C120770815 @default.
- W175064070 hasConcept C126322002 @default.
- W175064070 hasConcept C12722491 @default.
- W175064070 hasConcept C157767197 @default.
- W175064070 hasConcept C158846371 @default.
- W175064070 hasConcept C164705383 @default.
- W175064070 hasConcept C178853913 @default.
- W175064070 hasConcept C185592680 @default.
- W175064070 hasConcept C2779482390 @default.
- W175064070 hasConcept C2780959883 @default.
- W175064070 hasConcept C42219234 @default.
- W175064070 hasConcept C58245268 @default.
- W175064070 hasConcept C71924100 @default.
- W175064070 hasConcept C84393581 @default.
- W175064070 hasConceptScore W175064070C120770815 @default.
- W175064070 hasConceptScore W175064070C126322002 @default.
- W175064070 hasConceptScore W175064070C12722491 @default.
- W175064070 hasConceptScore W175064070C157767197 @default.
- W175064070 hasConceptScore W175064070C158846371 @default.
- W175064070 hasConceptScore W175064070C164705383 @default.
- W175064070 hasConceptScore W175064070C178853913 @default.
- W175064070 hasConceptScore W175064070C185592680 @default.
- W175064070 hasConceptScore W175064070C2779482390 @default.
- W175064070 hasConceptScore W175064070C2780959883 @default.
- W175064070 hasConceptScore W175064070C42219234 @default.
- W175064070 hasConceptScore W175064070C58245268 @default.
- W175064070 hasConceptScore W175064070C71924100 @default.
- W175064070 hasConceptScore W175064070C84393581 @default.
- W175064070 hasIssue "6" @default.
- W175064070 hasLocation W1750640701 @default.
- W175064070 hasLocation W1750640702 @default.
- W175064070 hasOpenAccess W175064070 @default.
- W175064070 hasPrimaryLocation W1750640701 @default.
- W175064070 hasRelatedWork W175064070 @default.
- W175064070 hasRelatedWork W1795150288 @default.
- W175064070 hasRelatedWork W1918378567 @default.
- W175064070 hasRelatedWork W2038658388 @default.
- W175064070 hasRelatedWork W2358670732 @default.
- W175064070 hasRelatedWork W2372214266 @default.
- W175064070 hasRelatedWork W2418108015 @default.
- W175064070 hasRelatedWork W2419624958 @default.
- W175064070 hasRelatedWork W252230469 @default.
- W175064070 hasRelatedWork W2884413031 @default.
- W175064070 hasVolume "264" @default.
- W175064070 isParatext "false" @default.
- W175064070 isRetracted "false" @default.
- W175064070 magId "175064070" @default.
- W175064070 workType "article" @default.