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- W175074118 abstract "The immunologic, cytogenetic and molecular data from a patient with Sézary syndrome are reported. Immunohistochemical analysis disclosed 90% helper CD4 cells and 10% CD8 cells. One of the most significant cytogenetic abnormalities was a t(7; 14) translocation at the level of the 7p13-15 and 14q11 bands, just where the T-cell receptors are located. At the molecular level, rearrangements of the alpha (in 14q11 chromosome), beta (in the 7q32) and gamma (in the 7p15) receptors were found. The translocation between chromosomes 7 and 14, at the level of the mentioned bands, could be responsible for some of the rearrangements found at the molecular level." @default.
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- W175074118 date "1989-06-17" @default.
- W175074118 modified "2023-09-25" @default.
- W175074118 title "[Sézary syndrome: morpho-immuno-phenotypic, cytogenetic and molecular characterization]." @default.
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