FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1750971820> ?p ?o ?g. }

• W1750971820 endingPage "7564" @default.
• W1750971820 startingPage "7552" @default.
• W1750971820 abstract "The acquisition of distinct neuronal fates is fundamental for the function of the cerebral cortex. We find that the development of subcerebral projections from layer 5 neurons in the mouse neocortex depends on the high levels of expression of the transcription factor CTIP1; CTIP1 is coexpressed with CTIP2 in neurons that project to subcerebral targets and with SATB2 in those that project to the contralateral cortex. CTIP1 directly represses Tbr1 in layer 5, which appears as a critical step for the acquisition of the subcerebral fate. In contrast, lower levels of CTIP1 in layer 6 are required for TBR1 expression, which directs the corticothalamic fate. CTIP1 does not appear to play a critical role in the acquisition of the callosal projection fate in layer 5. These findings unravel a key step in the acquisition of cell fate for closely related corticofugal neurons and indicate that differential dosages of transcriptions factors are critical to specify different neuronal identities." @default.
• W1750971820 created "2016-06-24" @default.
• W1750971820 creator A5003717573 @default.
• W1750971820 creator A5012717530 @default.
• W1750971820 creator A5023096253 @default.
• W1750971820 creator A5023096335 @default.
• W1750971820 creator A5027901497 @default.
• W1750971820 creator A5039888793 @default.
• W1750971820 creator A5040229050 @default.
• W1750971820 creator A5058722649 @default.
• W1750971820 creator A5064838256 @default.
• W1750971820 creator A5078868000 @default.
• W1750971820 date "2015-05-13" @default.
• W1750971820 modified "2023-10-10" @default.
• W1750971820 title "The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a" @default.
• W1750971820 cites W1605787076 @default.
• W1750971820 cites W1967491977 @default.
• W1750971820 cites W1968165696 @default.
• W1750971820 cites W1968800607 @default.
• W1750971820 cites W1969906780 @default.
• W1750971820 cites W1973065326 @default.
• W1750971820 cites W1973938821 @default.
• W1750971820 cites W1974374273 @default.
• W1750971820 cites W1979216961 @default.
• W1750971820 cites W1981590299 @default.
• W1750971820 cites W1989570444 @default.
• W1750971820 cites W1990935914 @default.
• W1750971820 cites W1998167494 @default.
• W1750971820 cites W2005843872 @default.
• W1750971820 cites W2007949444 @default.
• W1750971820 cites W2012994927 @default.
• W1750971820 cites W2025868352 @default.
• W1750971820 cites W2029245198 @default.
• W1750971820 cites W2035022202 @default.
• W1750971820 cites W2035738127 @default.
• W1750971820 cites W2044699614 @default.
• W1750971820 cites W2046165140 @default.
• W1750971820 cites W2047241508 @default.
• W1750971820 cites W2052407893 @default.
• W1750971820 cites W2053955820 @default.
• W1750971820 cites W2056554423 @default.
• W1750971820 cites W2061405862 @default.
• W1750971820 cites W2069977787 @default.
• W1750971820 cites W2070876549 @default.
• W1750971820 cites W2074076965 @default.
• W1750971820 cites W2089397711 @default.
• W1750971820 cites W2089990273 @default.
• W1750971820 cites W2092195277 @default.
• W1750971820 cites W2098027759 @default.
• W1750971820 cites W2105895439 @default.
• W1750971820 cites W2107277218 @default.
• W1750971820 cites W2108464868 @default.
• W1750971820 cites W2109726419 @default.
• W1750971820 cites W2110387447 @default.
• W1750971820 cites W2110710127 @default.
• W1750971820 cites W2113267995 @default.
• W1750971820 cites W2114353262 @default.
• W1750971820 cites W2116476971 @default.
• W1750971820 cites W2119324444 @default.
• W1750971820 cites W2124289307 @default.
• W1750971820 cites W2134881764 @default.
• W1750971820 cites W2137608891 @default.
• W1750971820 cites W2142565835 @default.
• W1750971820 cites W2147609224 @default.
• W1750971820 cites W2161637163 @default.
• W1750971820 cites W2165497651 @default.
• W1750971820 cites W2171995536 @default.
• W1750971820 cites W2192080449 @default.
• W1750971820 cites W2234814159 @default.
• W1750971820 cites W2239384431 @default.
• W1750971820 doi "https://doi.org/10.1523/jneurosci.0169-15.2015" @default.
• W1750971820 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6705430" @default.
• W1750971820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25972180" @default.
• W1750971820 hasPublicationYear "2015" @default.
• W1750971820 type Work @default.
• W1750971820 sameAs 1750971820 @default.
• W1750971820 citedByCount "48" @default.
• W1750971820 countsByYear W17509718202015 @default.
• W1750971820 countsByYear W17509718202016 @default.
• W1750971820 countsByYear W17509718202017 @default.
• W1750971820 countsByYear W17509718202018 @default.
• W1750971820 countsByYear W17509718202019 @default.
• W1750971820 countsByYear W17509718202020 @default.
• W1750971820 countsByYear W17509718202021 @default.
• W1750971820 countsByYear W17509718202022 @default.
• W1750971820 countsByYear W17509718202023 @default.
• W1750971820 crossrefType "journal-article" @default.
• W1750971820 hasAuthorship W1750971820A5003717573 @default.
• W1750971820 hasAuthorship W1750971820A5012717530 @default.
• W1750971820 hasAuthorship W1750971820A5023096253 @default.
• W1750971820 hasAuthorship W1750971820A5023096335 @default.
• W1750971820 hasAuthorship W1750971820A5027901497 @default.
• W1750971820 hasAuthorship W1750971820A5039888793 @default.
• W1750971820 hasAuthorship W1750971820A5040229050 @default.
• W1750971820 hasAuthorship W1750971820A5058722649 @default.
• W1750971820 hasAuthorship W1750971820A5064838256 @default.
• W1750971820 hasAuthorship W1750971820A5078868000 @default.
• W1750971820 hasBestOaLocation W17509718201 @default.

• next