Matches in SemOpenAlex for { <https://semopenalex.org/work/W1752203810> ?p ?o ?g. }
- W1752203810 endingPage "4958" @default.
- W1752203810 startingPage "4953" @default.
- W1752203810 abstract "Using a cell-free system for UV mutagenesis we have recently shown that extracts prepared from Escherichia coli cells promote a UV mutagenesis pathway that depends on the uvrABC repair genes independent of DNA replication (type II UV mutagenesis; Cohen-Fix, O., and Livneh, Z. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 3300-3304). Type II UV mutagenesis was defective also in extracts prepared from a uvrD strain. These deficiencies were complemented by adding purified UvrA, UvrB, UvrC, or UvrD proteins to the respective cell extracts. The Uvr proteins act at an early stage in the process, probably preparing a premutagenic single-stranded DNA gap, which subsequently serves as a substrate for the mutagenic reaction. Type II UV mutagenesis was not dependent on DNA polymerases I or on DNA polymerase II, but it was dependent on DNA polymerase III. Thus, similar to the in vivo situation, only DNA polymerase III is essential for UV mutagenesis. Antibodies against the beta subunit of DNA polymerase III holoenzyme inhibited DNA replication but not UV mutagenesis. Thus, the processivity subunit of the holoenzyme is not required for type II UV mutagenesis, in agreement with a mechanism involving filling-in of short single-stranded DNA gaps." @default.
- W1752203810 created "2016-06-24" @default.
- W1752203810 creator A5019022702 @default.
- W1752203810 creator A5073295537 @default.
- W1752203810 date "1994-02-01" @default.
- W1752203810 modified "2023-09-29" @default.
- W1752203810 title "In vitro UV mutagenesis associated with nucleotide excision-repair gaps in Escherichia coli." @default.
- W1752203810 cites W1483750611 @default.
- W1752203810 cites W1493097357 @default.
- W1752203810 cites W1532856669 @default.
- W1752203810 cites W1535843470 @default.
- W1752203810 cites W1548939450 @default.
- W1752203810 cites W1549704609 @default.
- W1752203810 cites W1551254087 @default.
- W1752203810 cites W1560835792 @default.
- W1752203810 cites W1569605331 @default.
- W1752203810 cites W1574275716 @default.
- W1752203810 cites W1575133253 @default.
- W1752203810 cites W1605051968 @default.
- W1752203810 cites W1653821563 @default.
- W1752203810 cites W1663226981 @default.
- W1752203810 cites W170319054 @default.
- W1752203810 cites W1755135846 @default.
- W1752203810 cites W1843973938 @default.
- W1752203810 cites W1903000287 @default.
- W1752203810 cites W1923728284 @default.
- W1752203810 cites W1925074773 @default.
- W1752203810 cites W1968724116 @default.
- W1752203810 cites W1974457967 @default.
- W1752203810 cites W1979850858 @default.
- W1752203810 cites W1982158185 @default.
- W1752203810 cites W1994203491 @default.
- W1752203810 cites W1995736991 @default.
- W1752203810 cites W1996566251 @default.
- W1752203810 cites W1998392368 @default.
- W1752203810 cites W2001132933 @default.
- W1752203810 cites W2001949463 @default.
- W1752203810 cites W2001952964 @default.
- W1752203810 cites W2006829375 @default.
- W1752203810 cites W2036501157 @default.
- W1752203810 cites W2040841668 @default.
- W1752203810 cites W2041787577 @default.
- W1752203810 cites W2042124972 @default.
- W1752203810 cites W2049301502 @default.
- W1752203810 cites W2056393864 @default.
- W1752203810 cites W2065014822 @default.
- W1752203810 cites W2065481190 @default.
- W1752203810 cites W2069716012 @default.
- W1752203810 cites W2071912871 @default.
- W1752203810 cites W2075633498 @default.
- W1752203810 cites W2087078419 @default.
- W1752203810 cites W2091155822 @default.
- W1752203810 cites W2091231611 @default.
- W1752203810 cites W2097883345 @default.
- W1752203810 cites W2115895870 @default.
- W1752203810 cites W2118128934 @default.
- W1752203810 cites W2123846442 @default.
- W1752203810 cites W2151546745 @default.
- W1752203810 cites W2173962436 @default.
- W1752203810 doi "https://doi.org/10.1016/s0021-9258(17)37638-x" @default.
- W1752203810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8106470" @default.
- W1752203810 hasPublicationYear "1994" @default.
- W1752203810 type Work @default.
- W1752203810 sameAs 1752203810 @default.
- W1752203810 citedByCount "23" @default.
- W1752203810 countsByYear W17522038102012 @default.
- W1752203810 countsByYear W17522038102017 @default.
- W1752203810 countsByYear W17522038102020 @default.
- W1752203810 countsByYear W17522038102021 @default.
- W1752203810 crossrefType "journal-article" @default.
- W1752203810 hasAuthorship W1752203810A5019022702 @default.
- W1752203810 hasAuthorship W1752203810A5073295537 @default.
- W1752203810 hasBestOaLocation W17522038101 @default.
- W1752203810 hasConcept C103408237 @default.
- W1752203810 hasConcept C104317684 @default.
- W1752203810 hasConcept C104451858 @default.
- W1752203810 hasConcept C131140672 @default.
- W1752203810 hasConcept C134935766 @default.
- W1752203810 hasConcept C143065580 @default.
- W1752203810 hasConcept C153911025 @default.
- W1752203810 hasConcept C156719811 @default.
- W1752203810 hasConcept C16318435 @default.
- W1752203810 hasConcept C164965036 @default.
- W1752203810 hasConcept C2756471 @default.
- W1752203810 hasConcept C31254050 @default.
- W1752203810 hasConcept C49105822 @default.
- W1752203810 hasConcept C501734568 @default.
- W1752203810 hasConcept C552990157 @default.
- W1752203810 hasConcept C55493867 @default.
- W1752203810 hasConcept C73573662 @default.
- W1752203810 hasConcept C76535049 @default.
- W1752203810 hasConcept C82381507 @default.
- W1752203810 hasConcept C86803240 @default.
- W1752203810 hasConcept C88354546 @default.
- W1752203810 hasConceptScore W1752203810C103408237 @default.
- W1752203810 hasConceptScore W1752203810C104317684 @default.
- W1752203810 hasConceptScore W1752203810C104451858 @default.
- W1752203810 hasConceptScore W1752203810C131140672 @default.