Matches in SemOpenAlex for { <https://semopenalex.org/work/W175530286> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W175530286 abstract "It has been suggested that the capacity to evolve can itself evolve. One factor that may be important in determining evolvability is modularity of the genotype-phenotype map. A related phenomenon is modularity in genome architecture, in which genes with epistatic effects are colocalized on the chromosome. This changes a population’s response to recombination by maximizing recombination among genes with additive effects and minimizing recombination of genes with epistatic interactions. The effects and origins of genome modularity were investigated using a computational model, in which a population of individuals evolved in a changing fitness landscape under mutation and recombination. Populations with modular genomes evolved faster than did populations with non-modular genomes. Moreover, in long runs that started with nonmodular genomes but allowed inversion, populations evolved high levels of genome modularity. This demonstrates that over long time periods, evolvability can itself evolve through reorganization of the genome. The results may explain some observations of genome modularity in bacteria and other organisms." @default.
- W175530286 created "2016-06-24" @default.
- W175530286 creator A5044191518 @default.
- W175530286 date "2000-01-01" @default.
- W175530286 modified "2023-09-27" @default.
- W175530286 title "The evolution of modularity in genome architecture" @default.
- W175530286 cites W1497256448 @default.
- W175530286 cites W2107424557 @default.
- W175530286 cites W2126074998 @default.
- W175530286 hasPublicationYear "2000" @default.
- W175530286 type Work @default.
- W175530286 sameAs 175530286 @default.
- W175530286 citedByCount "9" @default.
- W175530286 countsByYear W1755302862012 @default.
- W175530286 countsByYear W1755302862013 @default.
- W175530286 crossrefType "journal-article" @default.
- W175530286 hasAuthorship W175530286A5044191518 @default.
- W175530286 hasConcept C104317684 @default.
- W175530286 hasConcept C141231307 @default.
- W175530286 hasConcept C144024400 @default.
- W175530286 hasConcept C149923435 @default.
- W175530286 hasConcept C176147130 @default.
- W175530286 hasConcept C2779478453 @default.
- W175530286 hasConcept C2908647359 @default.
- W175530286 hasConcept C54355233 @default.
- W175530286 hasConcept C61727976 @default.
- W175530286 hasConcept C70721500 @default.
- W175530286 hasConcept C78458016 @default.
- W175530286 hasConcept C86803240 @default.
- W175530286 hasConceptScore W175530286C104317684 @default.
- W175530286 hasConceptScore W175530286C141231307 @default.
- W175530286 hasConceptScore W175530286C144024400 @default.
- W175530286 hasConceptScore W175530286C149923435 @default.
- W175530286 hasConceptScore W175530286C176147130 @default.
- W175530286 hasConceptScore W175530286C2779478453 @default.
- W175530286 hasConceptScore W175530286C2908647359 @default.
- W175530286 hasConceptScore W175530286C54355233 @default.
- W175530286 hasConceptScore W175530286C61727976 @default.
- W175530286 hasConceptScore W175530286C70721500 @default.
- W175530286 hasConceptScore W175530286C78458016 @default.
- W175530286 hasConceptScore W175530286C86803240 @default.
- W175530286 hasLocation W1755302861 @default.
- W175530286 hasOpenAccess W175530286 @default.
- W175530286 hasPrimaryLocation W1755302861 @default.
- W175530286 hasRelatedWork W1976586234 @default.
- W175530286 hasRelatedWork W1989208495 @default.
- W175530286 hasRelatedWork W1991874182 @default.
- W175530286 hasRelatedWork W1996705261 @default.
- W175530286 hasRelatedWork W2044821918 @default.
- W175530286 hasRelatedWork W2054730397 @default.
- W175530286 hasRelatedWork W2057494903 @default.
- W175530286 hasRelatedWork W2064559305 @default.
- W175530286 hasRelatedWork W2081967073 @default.
- W175530286 hasRelatedWork W2101756535 @default.
- W175530286 hasRelatedWork W2151538795 @default.
- W175530286 hasRelatedWork W2247230954 @default.
- W175530286 hasRelatedWork W2315181948 @default.
- W175530286 hasRelatedWork W2560253490 @default.
- W175530286 hasRelatedWork W2951829171 @default.
- W175530286 hasRelatedWork W3118680865 @default.
- W175530286 hasRelatedWork W3123589487 @default.
- W175530286 hasRelatedWork W2104305396 @default.
- W175530286 hasRelatedWork W3140515012 @default.
- W175530286 isParatext "false" @default.
- W175530286 isRetracted "false" @default.
- W175530286 magId "175530286" @default.
- W175530286 workType "article" @default.