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- W1755693722 abstract "Cholesterol synthesis in cell culture in the presence of D2O yields a spectrum of enriched molecules having a relative abundance that indicates random substitution of deuterium for hydrogen. Quantitation of the absolute rate of cholesterol synthesis is obtained by isotope ratio mass spectrometry. Mevinolin and 26-hydroxycholesterol both decrease cholesterol synthesis rate but have a discordant effect on HMG-CoA reductase activity." @default.
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- W1755693722 date "1985-08-01" @default.
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- W1755693722 title "Cholesterol metabolism: use of D2O for determination of synthesis rate in cell culture." @default.
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- W1755693722 doi "https://doi.org/10.1016/s0022-2275(20)34297-8" @default.
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