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- W1755855275 abstract "As biologists considering studies of scolytid genetics we are fortunate that an insect model exists that has been the target of analyses on both the individual and population levels for most of the twentieth century. The knowledge base associated with Drosophila melanogaster and congenerics is staggering, and it is a tribute to scientific inquiry that so much is known about organisms of such little economic importance. The goal of the classical crosses of D. melanogaster begun in the lab of T.H. Morgan in 1909 was to infer the basis of the phenotype (phenotype →a gene). The development of P-element-mediated transformation (Rubin and Spradling 1982) allows reverse genetic studies where the gene of choice is placed into the organism and the resulting individual is assayed to infer the phenotypic product of the gene (gene → phenotype). During the period between the advent of each of these approaches with Drosophila, serendipity and intensive screening procedures revealed a wide array of morphological, developmental, and behavioral mutants; biochemical studies characterized nucleic acids and proteins; studies led to the development of physical, cytological maps of polytene chromosomes; and, soon, the entire genome will be sequenced (Merriam and others 1991). The phenomenon of transposition (jumping genes) has been actively investigated in D. melanogaster (Green 1980, Engels 1983), and the transposons themselves have been the targets of studies of population genetics (Charlesworth and Langley 1989). In addition to the biochemical and molecular work, the drosophilids have been the subject of studies of population biology, phylogeny, and pheromone production (Bartlet and others 1986, Kaneshiro 1988, Singh 1989). In the Scolytidae, no mutants have been isolated, prospects for long-term culture have not been developed, most crosses have been performed to determine species status of wild populations rather than to assay for intraspecific phenotypic variants, and few biochemical reactions have been characterized. When evaluated against the background of Drosophila genetics, the status of scolytid genetics can be described as primitive at best. Thus, it is in an area of enormous opportunity, where," @default.
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- W1755855275 date "1992-01-01" @default.
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- W1755855275 title "The Status of Scolytid Genetics-A Reductionist's View" @default.
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