Matches in SemOpenAlex for { <https://semopenalex.org/work/W1756613609> ?p ?o ?g. }
- W1756613609 endingPage "9" @default.
- W1756613609 startingPage "175" @default.
- W1756613609 abstract "Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tropical regions of East, Central, and West Africa. Although epidemiological studies are lacking, hypertrophic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy seem to have characteristics similar to those of other populations elsewhere in the world. Recent advances in the genetic analysis of DCM in other parts of the world indicate that it is a genetically heterogeneous disorder in which some cases have a Mendelian cause and others have a non-genetic or multifactorial cause. This heterogeneous pattern of inheritance has been confirmed in small studies that have been conducted so far in Africa. The advent of human immunodeficiency virus infection and its association with cardiomyopathy has emphasised the role of inflammatory agents in the pathogenesis of DCM. By contrast with DCM in which some cases have major genetic contributions, there is scanty evidence for the role of genetic factors in the aetiology of EMF. Although the pathogenesis of EMF is not fully understood, it appears that the conditioning factor may be geography (in its widest sense, to include climate and socio-economic status), the triggering factor may be an as yet unidentified infective agent, and the perpetuating factor may be eosinophilia. There is a need for renewed effort to identify genetic and non-genetic factors in EMF and other forms of heart muscle disease that are prevalent on the continent of Africa." @default.
- W1756613609 created "2016-06-24" @default.
- W1756613609 creator A5006647748 @default.
- W1756613609 creator A5025153608 @default.
- W1756613609 date "2007-07-07" @default.
- W1756613609 modified "2023-09-27" @default.
- W1756613609 title "Cardiomyopathy in Africa: heredity versus environment." @default.
- W1756613609 cites W1495588184 @default.
- W1756613609 cites W1586021722 @default.
- W1756613609 cites W1972119387 @default.
- W1756613609 cites W1977371766 @default.
- W1756613609 cites W1980620195 @default.
- W1756613609 cites W1983280924 @default.
- W1756613609 cites W2003377951 @default.
- W1756613609 cites W2008751355 @default.
- W1756613609 cites W2010224540 @default.
- W1756613609 cites W2014157289 @default.
- W1756613609 cites W2025251141 @default.
- W1756613609 cites W2028749648 @default.
- W1756613609 cites W2036248349 @default.
- W1756613609 cites W2039237774 @default.
- W1756613609 cites W2039923961 @default.
- W1756613609 cites W2057999178 @default.
- W1756613609 cites W2080836283 @default.
- W1756613609 cites W2089302271 @default.
- W1756613609 cites W2093548393 @default.
- W1756613609 cites W2100651399 @default.
- W1756613609 cites W2102913313 @default.
- W1756613609 cites W2120792422 @default.
- W1756613609 cites W2124719378 @default.
- W1756613609 cites W2129208982 @default.
- W1756613609 cites W2135718528 @default.
- W1756613609 cites W2135831025 @default.
- W1756613609 cites W2135849060 @default.
- W1756613609 cites W2145441281 @default.
- W1756613609 cites W2155121555 @default.
- W1756613609 cites W2157800900 @default.
- W1756613609 cites W2162978423 @default.
- W1756613609 cites W2167259218 @default.
- W1756613609 cites W2186302415 @default.
- W1756613609 cites W2194305936 @default.
- W1756613609 cites W2315633478 @default.
- W1756613609 cites W2320264340 @default.
- W1756613609 cites W2428596886 @default.
- W1756613609 cites W4205398740 @default.
- W1756613609 cites W4250025891 @default.
- W1756613609 cites W70822732 @default.
- W1756613609 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4213757" @default.
- W1756613609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17612750" @default.
- W1756613609 hasPublicationYear "2007" @default.
- W1756613609 type Work @default.
- W1756613609 sameAs 1756613609 @default.
- W1756613609 citedByCount "20" @default.
- W1756613609 countsByYear W17566136092012 @default.
- W1756613609 countsByYear W17566136092013 @default.
- W1756613609 countsByYear W17566136092016 @default.
- W1756613609 countsByYear W17566136092017 @default.
- W1756613609 countsByYear W17566136092021 @default.
- W1756613609 countsByYear W17566136092022 @default.
- W1756613609 countsByYear W17566136092023 @default.
- W1756613609 crossrefType "journal-article" @default.
- W1756613609 hasAuthorship W1756613609A5006647748 @default.
- W1756613609 hasAuthorship W1756613609A5025153608 @default.
- W1756613609 hasConcept C104317684 @default.
- W1756613609 hasConcept C126322002 @default.
- W1756613609 hasConcept C143098186 @default.
- W1756613609 hasConcept C175783326 @default.
- W1756613609 hasConcept C2776383484 @default.
- W1756613609 hasConcept C2778198053 @default.
- W1756613609 hasConcept C2778797674 @default.
- W1756613609 hasConcept C2779134260 @default.
- W1756613609 hasConcept C2779962030 @default.
- W1756613609 hasConcept C2780559512 @default.
- W1756613609 hasConcept C2780942790 @default.
- W1756613609 hasConcept C3018878892 @default.
- W1756613609 hasConcept C54355233 @default.
- W1756613609 hasConcept C71924100 @default.
- W1756613609 hasConcept C86803240 @default.
- W1756613609 hasConceptScore W1756613609C104317684 @default.
- W1756613609 hasConceptScore W1756613609C126322002 @default.
- W1756613609 hasConceptScore W1756613609C143098186 @default.
- W1756613609 hasConceptScore W1756613609C175783326 @default.
- W1756613609 hasConceptScore W1756613609C2776383484 @default.
- W1756613609 hasConceptScore W1756613609C2778198053 @default.
- W1756613609 hasConceptScore W1756613609C2778797674 @default.
- W1756613609 hasConceptScore W1756613609C2779134260 @default.
- W1756613609 hasConceptScore W1756613609C2779962030 @default.
- W1756613609 hasConceptScore W1756613609C2780559512 @default.
- W1756613609 hasConceptScore W1756613609C2780942790 @default.
- W1756613609 hasConceptScore W1756613609C3018878892 @default.
- W1756613609 hasConceptScore W1756613609C54355233 @default.
- W1756613609 hasConceptScore W1756613609C71924100 @default.
- W1756613609 hasConceptScore W1756613609C86803240 @default.
- W1756613609 hasIssue "3" @default.
- W1756613609 hasLocation W17566136091 @default.
- W1756613609 hasOpenAccess W1756613609 @default.
- W1756613609 hasPrimaryLocation W17566136091 @default.
- W1756613609 hasRelatedWork W121888249 @default.