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- W1756613815 abstract "A 39-year-old woman, had a lesion on her right thigh that first developed when she was 6 weeks old. This lesion was said to have resembled “spider bites,” and was initially treated with cryotherapy. It continued to enlarge and was biopsied in May 1969, when she was 13 years old. The patient was told she had “neurofibroma.” In 1971, the lesion was rebiopsied and a question of a sarcoma was raised in the pathology report. She underwent extensive surgery to remove the lesion, requiring a skin graft at the operation sife. Multiple lesions subsequently developed around her graft. Biopsies of several lesions were interpreted as dermatofibroma, and she was referred to the Indiana University, Department of Dermatology. When seen in 1995, she had a well-healed 30 cmx14 cm hypopigmenfed split-thickness skin graft present on the lateral right thigh. The margin of the graft was outlined by multiple red-brown firm papules and plaques. Some of the papules and plaques extended beyond the margin of the graft by several centimeters (Fig. 1). Histopathology of the satellite lesions showed epidermal hyperplasia and diffuse spindle cell proliferation in the upper and lower dermis (Fig. 2). The majority of the spindle cells stained positively for Factor Xllla (a marker for dermal dendrocytes). They did not stain with CD34 (a marker for dermatofibrosarcoma protuberans)." @default.
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- W1756613815 date "1997-09-01" @default.
- W1756613815 modified "2023-10-07" @default.
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- W1756613815 doi "https://doi.org/10.1046/j.1365-4362.1997.00173.x" @default.
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