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- W1758077385 abstract "The aims of this research were to study the effects of giving natrium cyclamate orally on rat’s (Rattus norvegicus L.) hematocryte value, Hb, erythrocyte and leukocyte number, Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), and the erythrocyte and leukocyte morphology. For these purposes, natrium cyclamate was treated orally to rats (Rattus norvegicus L.) within 30 days. The framework of this research is that natrium cyclamate, which is given orally to rats, will enter the digestorial tract, goes into the circulatorial system and influences hematological characteristics. In this research, Complete Random Design with 5 experimental categories i.e.: 2 ml akuades/200 g body weight as the control, 4,5 mg natrium cyclamate/200 g body weight; 9,5 mg natrium cyclamate/200 g body weight; 14,5 mg natrium cyclamate/200 g body weight and 19,5 mg natrium cyclamate/200 g body weight was used in this experiment. The observations included in the hematocryte value, Hb, erythrocyte and leukocyte number, MCV, MCH and MCHC. The data resulted were analyzed by Analysis of Variance and DMRT. Morphology of erythrocyte and leukocyte was analyzed qualitatively. The result showed that the treatment of natrium cyclamate in 19,5 mg/200 body weight’s dosage decreased hematocryte value; 4,5 mg natrium cyclamate/200 body weight, 9,5 mg natrium cyclamate/200 body weight and 14,5 mg natrium cyclamate/200 body weight’s dosages decreased Hb; 9,5 mg natrium cyclamate/200 g body weight 14,5 mg natrium cyclamate/200 body weight and 19,5 mg natrium cyclamate/200 body weight's dosages reduced erythrocyte number and increased leukocyte number. It can be concluded that the treatment of various dosages of natrium cyclamate could change the erythrocyte and leukocyte morphology. Key words: natrium cyclamate, rat (Rattus noregicus L.), hematological characteristics." @default.
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- W1758077385 date "2003-01-01" @default.
- W1758077385 modified "2023-09-24" @default.
- W1758077385 title "The effects of giving natrium cyclamate orally on rat’s (Rattus norvegicus L.) hematological characteristics" @default.
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