FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1759876686> ?p ?o ?g. }

• W1759876686 endingPage "7620" @default.
• W1759876686 startingPage "7611" @default.
• W1759876686 abstract "The structure of lactate dehydrogenase isoenzyme C4 from mouse testes was solved at 2.9 A resolution using the technique of molecular replacement. The electron density map revealed a ternary-like configuration of the flexible loop peptide although density corresponding to the coenzyme and substrate molecules was not present. Apparently the apo-lactate dehydrogenase molecule in solution is in a dynamic equilibrium between the O (loop open as found in dogfish apo-lactate dehydrogenase M4) and C (loop closed as found in a variety of ternary complexes) conformations. During crystallization of the apoenzyme one or the other conformers is selected. The apparent stability of the closed conformation for the apo-lactate dehydrogenase C4 molecule may in part explain the low catalytic turnover number of the C isoenzyme. A possible substitution of an arginine residue at position 30 may also be a contributing factor as well as allowing NADP to act as coenzyme." @default.
• W1759876686 created "2016-06-24" @default.
• W1759876686 creator A5067120865 @default.
• W1759876686 creator A5067497203 @default.
• W1759876686 date "1978-12-13" @default.
• W1759876686 modified "2023-09-26" @default.
• W1759876686 title "The structure of mouse testicular lactate dehydrogenase isoenzyme C4 at 2.9 A resolution." @default.
• W1759876686 cites W1489847725 @default.
• W1759876686 cites W1555353953 @default.
• W1759876686 cites W1778187549 @default.
• W1759876686 cites W1963967386 @default.
• W1759876686 cites W1965583422 @default.
• W1759876686 cites W1970208847 @default.
• W1759876686 cites W1982104865 @default.
• W1759876686 cites W1988499910 @default.
• W1759876686 cites W2004054583 @default.
• W1759876686 cites W2008106102 @default.
• W1759876686 cites W2024974377 @default.
• W1759876686 cites W2025290023 @default.
• W1759876686 cites W2031438022 @default.
• W1759876686 cites W2043021736 @default.
• W1759876686 cites W2047534394 @default.
• W1759876686 cites W2051416676 @default.
• W1759876686 cites W2052859627 @default.
• W1759876686 cites W2052971352 @default.
• W1759876686 cites W2062150500 @default.
• W1759876686 cites W2062606481 @default.
• W1759876686 cites W2074049284 @default.
• W1759876686 cites W2078720661 @default.
• W1759876686 cites W2089352451 @default.
• W1759876686 cites W2102934596 @default.
• W1759876686 cites W2112854926 @default.
• W1759876686 cites W2119035208 @default.
• W1759876686 cites W2126805362 @default.
• W1759876686 cites W2130213300 @default.
• W1759876686 cites W2155779310 @default.
• W1759876686 cites W2171453285 @default.
• W1759876686 cites W45602840 @default.
• W1759876686 doi "https://doi.org/10.2210/pdb1ldx/pdb" @default.
• W1759876686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/468772" @default.
• W1759876686 hasPublicationYear "1978" @default.
• W1759876686 type Work @default.
• W1759876686 sameAs 1759876686 @default.
• W1759876686 citedByCount "16" @default.
• W1759876686 crossrefType "component" @default.
• W1759876686 hasAuthorship W1759876686A5067120865 @default.
• W1759876686 hasAuthorship W1759876686A5067497203 @default.
• W1759876686 hasConcept C119795356 @default.
• W1759876686 hasConcept C178790620 @default.
• W1759876686 hasConcept C181199279 @default.
• W1759876686 hasConcept C185592680 @default.
• W1759876686 hasConcept C197957613 @default.
• W1759876686 hasConcept C2776317432 @default.
• W1759876686 hasConcept C2777166331 @default.
• W1759876686 hasConcept C2777318727 @default.
• W1759876686 hasConcept C2779268744 @default.
• W1759876686 hasConcept C32909587 @default.
• W1759876686 hasConcept C47701112 @default.
• W1759876686 hasConcept C55493867 @default.
• W1759876686 hasConcept C71240020 @default.
• W1759876686 hasConcept C8010536 @default.
• W1759876686 hasConcept C86756495 @default.
• W1759876686 hasConceptScore W1759876686C119795356 @default.
• W1759876686 hasConceptScore W1759876686C178790620 @default.
• W1759876686 hasConceptScore W1759876686C181199279 @default.
• W1759876686 hasConceptScore W1759876686C185592680 @default.
• W1759876686 hasConceptScore W1759876686C197957613 @default.
• W1759876686 hasConceptScore W1759876686C2776317432 @default.
• W1759876686 hasConceptScore W1759876686C2777166331 @default.
• W1759876686 hasConceptScore W1759876686C2777318727 @default.
• W1759876686 hasConceptScore W1759876686C2779268744 @default.
• W1759876686 hasConceptScore W1759876686C32909587 @default.
• W1759876686 hasConceptScore W1759876686C47701112 @default.
• W1759876686 hasConceptScore W1759876686C55493867 @default.
• W1759876686 hasConceptScore W1759876686C71240020 @default.
• W1759876686 hasConceptScore W1759876686C8010536 @default.
• W1759876686 hasConceptScore W1759876686C86756495 @default.
• W1759876686 hasIssue "16" @default.
• W1759876686 hasLocation W17598766861 @default.
• W1759876686 hasOpenAccess W1759876686 @default.
• W1759876686 hasPrimaryLocation W17598766861 @default.
• W1759876686 hasRelatedWork W1475495210 @default.
• W1759876686 hasRelatedWork W1508157641 @default.
• W1759876686 hasRelatedWork W1524513887 @default.
• W1759876686 hasRelatedWork W1555353953 @default.
• W1759876686 hasRelatedWork W1575907658 @default.
• W1759876686 hasRelatedWork W1963967386 @default.
• W1759876686 hasRelatedWork W1966041739 @default.
• W1759876686 hasRelatedWork W1988499910 @default.
• W1759876686 hasRelatedWork W1990561769 @default.
• W1759876686 hasRelatedWork W2009909634 @default.
• W1759876686 hasRelatedWork W2024974377 @default.
• W1759876686 hasRelatedWork W2047889953 @default.
• W1759876686 hasRelatedWork W2052971352 @default.
• W1759876686 hasRelatedWork W2059834438 @default.
• W1759876686 hasRelatedWork W2076246553 @default.
• W1759876686 hasRelatedWork W2083922038 @default.
• W1759876686 hasRelatedWork W2102488038 @default.

• next