Matches in SemOpenAlex for { <https://semopenalex.org/work/W1760436872> ?p ?o ?g. }
- W1760436872 endingPage "30327" @default.
- W1760436872 startingPage "30318" @default.
- W1760436872 abstract "We have studied the interaction of a polymeric water soluble anthracenyl derivative () with salmon testes DNA. The results from UV-Vis, fluorescence, Fourier transform infrared (FT-IR) and circular dichroism spectroscopies indicate that the groove binding process regulates the interaction between and DNA. The binding constants, calculated by absorption spectroscopy at 298, 304 and 310 K, were equal to 3.2 × 10(5) M(-1), 4.7 × 10(5) M(-1), and 6.6 × 10(5) M(-1) respectively, proving a relatively high affinity of for salmon testes DNA. Results of Hoechst 33258 displacement assays strongly support the groove binding mode of to DNA. The association stoichiometry of the :DNA adduct was found to be 1 for every 5 base pairs. FT-IR spectra, recorded at different /DNA molar ratios, indicate the involvement of the phosphate groups and adenine and thymine DNA bases in the association process. Thermodynamic results suggest that hydrophobic forces regulate the binding of with DNA without excluding some extent of involvement of van der Waals forces and hydrogen bonding arising due to surface binding between the hydrophilic polymeric arms of the ligand and the functional groups positioned on the edge of the groove. The resulting composite biomaterial could constitute a valuable candidate for future biological and/or photonic applications." @default.
- W1760436872 created "2016-06-24" @default.
- W1760436872 creator A5020841596 @default.
- W1760436872 creator A5022353869 @default.
- W1760436872 creator A5023143190 @default.
- W1760436872 creator A5047676205 @default.
- W1760436872 creator A5051797024 @default.
- W1760436872 creator A5059086042 @default.
- W1760436872 creator A5073967201 @default.
- W1760436872 creator A5075475675 @default.
- W1760436872 creator A5082105691 @default.
- W1760436872 date "2015-01-01" @default.
- W1760436872 modified "2023-09-28" @default.
- W1760436872 title "Interactions of a biocompatible water-soluble anthracenyl polymer derivative with double-stranded DNA" @default.
- W1760436872 cites W1515935592 @default.
- W1760436872 cites W1523096735 @default.
- W1760436872 cites W1530014088 @default.
- W1760436872 cites W1593173232 @default.
- W1760436872 cites W1913218312 @default.
- W1760436872 cites W1963725477 @default.
- W1760436872 cites W1966387745 @default.
- W1760436872 cites W1973489116 @default.
- W1760436872 cites W1974589611 @default.
- W1760436872 cites W1975222435 @default.
- W1760436872 cites W1975361879 @default.
- W1760436872 cites W1977283538 @default.
- W1760436872 cites W1978831420 @default.
- W1760436872 cites W1978877629 @default.
- W1760436872 cites W1981147921 @default.
- W1760436872 cites W1982504159 @default.
- W1760436872 cites W1983338915 @default.
- W1760436872 cites W1985635100 @default.
- W1760436872 cites W1991262047 @default.
- W1760436872 cites W1992252389 @default.
- W1760436872 cites W1995992576 @default.
- W1760436872 cites W1998301685 @default.
- W1760436872 cites W1998340494 @default.
- W1760436872 cites W1998637008 @default.
- W1760436872 cites W2002909244 @default.
- W1760436872 cites W2010702739 @default.
- W1760436872 cites W2014862894 @default.
- W1760436872 cites W2015636882 @default.
- W1760436872 cites W2016503226 @default.
- W1760436872 cites W2016733166 @default.
- W1760436872 cites W2017679019 @default.
- W1760436872 cites W2018201383 @default.
- W1760436872 cites W2020092710 @default.
- W1760436872 cites W2020586725 @default.
- W1760436872 cites W2026200299 @default.
- W1760436872 cites W2027310997 @default.
- W1760436872 cites W2028520627 @default.
- W1760436872 cites W2029622237 @default.
- W1760436872 cites W2031493102 @default.
- W1760436872 cites W2037110024 @default.
- W1760436872 cites W2037444161 @default.
- W1760436872 cites W2038124483 @default.
- W1760436872 cites W2038985545 @default.
- W1760436872 cites W2044223479 @default.
- W1760436872 cites W2044420242 @default.
- W1760436872 cites W2044455775 @default.
- W1760436872 cites W2045489285 @default.
- W1760436872 cites W2047130228 @default.
- W1760436872 cites W2048853717 @default.
- W1760436872 cites W2048925647 @default.
- W1760436872 cites W2050042672 @default.
- W1760436872 cites W2053788103 @default.
- W1760436872 cites W2054077127 @default.
- W1760436872 cites W2055487676 @default.
- W1760436872 cites W2058569149 @default.
- W1760436872 cites W2058988354 @default.
- W1760436872 cites W2061591904 @default.
- W1760436872 cites W2064583588 @default.
- W1760436872 cites W2067906849 @default.
- W1760436872 cites W2072713474 @default.
- W1760436872 cites W2073696638 @default.
- W1760436872 cites W2075705506 @default.
- W1760436872 cites W2089899477 @default.
- W1760436872 cites W2095102225 @default.
- W1760436872 cites W2095335747 @default.
- W1760436872 cites W2102297924 @default.
- W1760436872 cites W2109535059 @default.
- W1760436872 cites W2129995310 @default.
- W1760436872 cites W2144483773 @default.
- W1760436872 cites W2146456435 @default.
- W1760436872 cites W2148550663 @default.
- W1760436872 cites W2162417581 @default.
- W1760436872 cites W2168923338 @default.
- W1760436872 cites W2173807279 @default.
- W1760436872 cites W2321972685 @default.
- W1760436872 cites W2330914321 @default.
- W1760436872 cites W2334368320 @default.
- W1760436872 cites W2506200838 @default.
- W1760436872 cites W265143682 @default.
- W1760436872 cites W3101210058 @default.
- W1760436872 doi "https://doi.org/10.1039/c5cp05381a" @default.
- W1760436872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26506886" @default.
- W1760436872 hasPublicationYear "2015" @default.
- W1760436872 type Work @default.