Matches in SemOpenAlex for { <https://semopenalex.org/work/W1761209412> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1761209412 endingPage "E523" @default.
- W1761209412 startingPage "E516" @default.
- W1761209412 abstract "We tested the validity of the use of [2-13C]glycerol and of the mass isotopomer distribution analysis of glucose for measuring gluconeogenesis in vitro and in vivo. When isolated rat livers (starved for 48 h) were infused with labeled glycerol without or with lactate+pyruvate, gluconeogenesis accounted for > 90% of glucose production. When glucose was added to the infusate so that glucose produced by the liver represented only 80 or 45% of total glucose output, this dilution could be calculated from the mass isotopomer distribution of glucose. When postabsorptive and starved rats were infused with [2-13C]glycerol, gluconeogenesis accounted for 54 +/- 2 and 89 +/- 1%, respectively, of glucose production. However, accurate measures could be obtained, particularly in postabsorptive rats, only with high tracer infusion rates (representing > or = 50% of endogenous glycerol production rate). In both groups of rats, these infusion rates resulted in an increase in total glycerol turnover rate and gluconeogenesis from glycerol. In addition, hepatic concentration of glycerol 3-phosphate was increased. In conclusion, [2-13C]glycerol infusion and mass isotopomer distribution analysis of glucose appear to be useful methods for studies of gluconeogenesis in vitro and in vivo; however, accurate measurements in vivo can be obtained only at the expense of some perturbation of the metabolic pathway studied." @default.
- W1761209412 created "2016-06-24" @default.
- W1761209412 creator A5016838496 @default.
- W1761209412 creator A5023894075 @default.
- W1761209412 creator A5088314972 @default.
- W1761209412 date "1995-09-01" @default.
- W1761209412 modified "2023-10-16" @default.
- W1761209412 title "Measuring gluconeogenesis with [2-13C]glycerol and mass isotopomer distribution analysis of glucose" @default.
- W1761209412 cites W1490420782 @default.
- W1761209412 cites W1572846506 @default.
- W1761209412 cites W1588593248 @default.
- W1761209412 cites W2072826100 @default.
- W1761209412 cites W2099563100 @default.
- W1761209412 cites W2105736904 @default.
- W1761209412 cites W2166716973 @default.
- W1761209412 cites W2335241585 @default.
- W1761209412 cites W6183424 @default.
- W1761209412 doi "https://doi.org/10.1152/ajpendo.1995.269.3.e516" @default.
- W1761209412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7573429" @default.
- W1761209412 hasPublicationYear "1995" @default.
- W1761209412 type Work @default.
- W1761209412 sameAs 1761209412 @default.
- W1761209412 citedByCount "28" @default.
- W1761209412 countsByYear W17612094122012 @default.
- W1761209412 countsByYear W17612094122014 @default.
- W1761209412 countsByYear W17612094122017 @default.
- W1761209412 countsByYear W17612094122018 @default.
- W1761209412 crossrefType "journal-article" @default.
- W1761209412 hasAuthorship W1761209412A5016838496 @default.
- W1761209412 hasAuthorship W1761209412A5023894075 @default.
- W1761209412 hasAuthorship W1761209412A5088314972 @default.
- W1761209412 hasConcept C126322002 @default.
- W1761209412 hasConcept C127124265 @default.
- W1761209412 hasConcept C134018914 @default.
- W1761209412 hasConcept C150903083 @default.
- W1761209412 hasConcept C165135838 @default.
- W1761209412 hasConcept C17093226 @default.
- W1761209412 hasConcept C178790620 @default.
- W1761209412 hasConcept C185592680 @default.
- W1761209412 hasConcept C207001950 @default.
- W1761209412 hasConcept C20904676 @default.
- W1761209412 hasConcept C2780881558 @default.
- W1761209412 hasConcept C32909587 @default.
- W1761209412 hasConcept C55493867 @default.
- W1761209412 hasConcept C62231903 @default.
- W1761209412 hasConcept C71924100 @default.
- W1761209412 hasConcept C86803240 @default.
- W1761209412 hasConceptScore W1761209412C126322002 @default.
- W1761209412 hasConceptScore W1761209412C127124265 @default.
- W1761209412 hasConceptScore W1761209412C134018914 @default.
- W1761209412 hasConceptScore W1761209412C150903083 @default.
- W1761209412 hasConceptScore W1761209412C165135838 @default.
- W1761209412 hasConceptScore W1761209412C17093226 @default.
- W1761209412 hasConceptScore W1761209412C178790620 @default.
- W1761209412 hasConceptScore W1761209412C185592680 @default.
- W1761209412 hasConceptScore W1761209412C207001950 @default.
- W1761209412 hasConceptScore W1761209412C20904676 @default.
- W1761209412 hasConceptScore W1761209412C2780881558 @default.
- W1761209412 hasConceptScore W1761209412C32909587 @default.
- W1761209412 hasConceptScore W1761209412C55493867 @default.
- W1761209412 hasConceptScore W1761209412C62231903 @default.
- W1761209412 hasConceptScore W1761209412C71924100 @default.
- W1761209412 hasConceptScore W1761209412C86803240 @default.
- W1761209412 hasIssue "3" @default.
- W1761209412 hasLocation W17612094121 @default.
- W1761209412 hasLocation W17612094122 @default.
- W1761209412 hasOpenAccess W1761209412 @default.
- W1761209412 hasPrimaryLocation W17612094121 @default.
- W1761209412 hasRelatedWork W1761209412 @default.
- W1761209412 hasRelatedWork W1986513039 @default.
- W1761209412 hasRelatedWork W2041949500 @default.
- W1761209412 hasRelatedWork W2046344380 @default.
- W1761209412 hasRelatedWork W2047888670 @default.
- W1761209412 hasRelatedWork W2063169804 @default.
- W1761209412 hasRelatedWork W2073389175 @default.
- W1761209412 hasRelatedWork W2133707772 @default.
- W1761209412 hasRelatedWork W2163066715 @default.
- W1761209412 hasRelatedWork W3199816176 @default.
- W1761209412 hasVolume "269" @default.
- W1761209412 isParatext "false" @default.
- W1761209412 isRetracted "false" @default.
- W1761209412 magId "1761209412" @default.
- W1761209412 workType "article" @default.