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• W1761322105 abstract "Suckling mice are protected against murine rotavirus-induced gastroenteritis after adoptive transfer of splenic lymphocytes from immunized animals. Adoptive transfer of Thy1(+)-depleted or CD8(+)-depleted lymphocytes abrogated protection against challenge. (We previously found that depletion of Thy1+ or CD8+ lymphocytes from rotavirus-immunized mice decreased rotavirus-specific cytotoxic activity in vitro.) Protection against disease occurred in the absence of rotavirus-specific neutralizing antibodies in the sera of suckling mice. Rotavirus-specific cytotoxic T lymphocytes may be important in either amelioration of acute infection or protection against reinfection." @default.
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• W1761322105 date "1990-12-01" @default.
• W1761322105 modified "2023-09-25" @default.
• W1761322105 title "Rotavirus-specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice" @default.
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• W1761322105 doi "https://doi.org/10.1128/jvi.64.12.6325-6328.1990" @default.
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