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- W176155751 abstract "Background: Associations between stress exposure and adiposity have been reported in adults, but data in children and adolescents are limited. Methods: The HELP trial is a randomized controlled trial of a motivational interviewing intervention for obese adolescents (12-19 years) recruited from the community (London, UK). Baseline data collection included anthropometry (n=174; 109 girls), awakening and 30-minute post-awakening salivary cortisol (n=155; 97 girls), and a validated stress questionnaire (A-FILE) completed by the adolescents (n=172; 108 girls). This study presents baseline data regarding stress and adiposity, as assessed by body mass index (BMI), BMI Z-score (UK 1990), fat mass (from bioelectrical impedance), and waist circumference. Associations between adiposity (outcome) and total recent stressful life events (A-FILE) and cortisol measures were tested with linear regression. Results: Overall, total recent stressful life events were positively associated with BMI, BMI z-score and fat mass (p=0.019-0.048). When stratified by sex, only the association of total recent stressful life events with BMI and fat mass in girls remained significant (Table 1). The magnitude of change in cortisol during 30 minutes post-awakening was negatively associated with BMI and BMI z-score in girls only (p<0.04; Table 2), but no associations were found with the total change in waking cortisol. Conclusions: Both physiological (cortisol) and psychological (total recent stressful life events) measures of stress were associated with BMI in obese adolescent girls (but not boys), and should be considered in clinical assessments. The direction of these associations is unclear, and requires longitudinal investigation." @default.
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- W176155751 date "2014-03-18" @default.
- W176155751 modified "2023-09-27" @default.
- W176155751 title "Associations of physiological and life-event measures of stress with adiposity in obese adolescents" @default.
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