Matches in SemOpenAlex for { <https://semopenalex.org/work/W1761921570> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1761921570 endingPage "1088" @default.
- W1761921570 startingPage "1079" @default.
- W1761921570 abstract "The present studies utilized the in vivo single-pass, luminally perfused intestinal segment model in rats to evaluate pyridoxine (PN) uptake under conditions that permitted prolonged exposure of mucosa to relatively constant PN concentrations. Perfusates contained [14C]PN, unlabeled PN, and [3H]polyethylene glycol in buffer. Uptake was constant for 1 h and correlated with water absorption. Uptake of 0.2 µM PN was highest in the duodenum, intermediate in the jejunum, and lowest in the ileum. When expressed as uptake/micromolar PN, uptake of 1 mM compared to 0.2 µM PN was decreased by 37.5% in duodenum (P < 0.001) and 14.4% in jejunum (P < 0.05); uptake/micromolar PN were similar in ileum. In duodenum saturable uptake was apparent for 2–100 µM PN and was not explainable by a membrane carrier, presence of bile or lumen-plasma concentration gradients. Conclusions were: uptake of PN by in vivo perfused intestinal segments decreases from proximal to distal; the greater uptake proximally was associated with a saturable component of uptake that was greatest in duodenum, less, but significant, in proximal jejunum and absent in distal ileum and saturation of uptake in the rat proximal small intestine was compatible with a role for mucosal metabolism of absorbed PN in the enhancement of uptake of PN at low luminal concentrations." @default.
- W1761921570 created "2016-06-24" @default.
- W1761921570 creator A5070357303 @default.
- W1761921570 date "1985-08-01" @default.
- W1761921570 modified "2023-10-16" @default.
- W1761921570 title "Uptake of Pyridoxine by in Vivo Perfused Segments of Rat Small Intestine: a Possible Role for Intracellular Vitamin Metabolism" @default.
- W1761921570 cites W1524284319 @default.
- W1761921570 cites W1888878395 @default.
- W1761921570 cites W1916344039 @default.
- W1761921570 cites W1959423865 @default.
- W1761921570 cites W1969954079 @default.
- W1761921570 cites W1988463430 @default.
- W1761921570 cites W1989390880 @default.
- W1761921570 cites W2125110448 @default.
- W1761921570 cites W2174764521 @default.
- W1761921570 cites W2329978146 @default.
- W1761921570 cites W2409294378 @default.
- W1761921570 cites W2460296029 @default.
- W1761921570 doi "https://doi.org/10.1093/jn/115.8.1079" @default.
- W1761921570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4020487" @default.
- W1761921570 hasPublicationYear "1985" @default.
- W1761921570 type Work @default.
- W1761921570 sameAs 1761921570 @default.
- W1761921570 citedByCount "26" @default.
- W1761921570 countsByYear W17619215702012 @default.
- W1761921570 countsByYear W17619215702015 @default.
- W1761921570 countsByYear W17619215702018 @default.
- W1761921570 countsByYear W17619215702020 @default.
- W1761921570 countsByYear W17619215702021 @default.
- W1761921570 crossrefType "journal-article" @default.
- W1761921570 hasAuthorship W1761921570A5070357303 @default.
- W1761921570 hasBestOaLocation W17619215701 @default.
- W1761921570 hasConcept C126322002 @default.
- W1761921570 hasConcept C134018914 @default.
- W1761921570 hasConcept C150903083 @default.
- W1761921570 hasConcept C185592680 @default.
- W1761921570 hasConcept C207001950 @default.
- W1761921570 hasConcept C2776366702 @default.
- W1761921570 hasConcept C2776514930 @default.
- W1761921570 hasConcept C2776809568 @default.
- W1761921570 hasConcept C2777226302 @default.
- W1761921570 hasConcept C2777882243 @default.
- W1761921570 hasConcept C3019368612 @default.
- W1761921570 hasConcept C62231903 @default.
- W1761921570 hasConcept C71924100 @default.
- W1761921570 hasConcept C86803240 @default.
- W1761921570 hasConceptScore W1761921570C126322002 @default.
- W1761921570 hasConceptScore W1761921570C134018914 @default.
- W1761921570 hasConceptScore W1761921570C150903083 @default.
- W1761921570 hasConceptScore W1761921570C185592680 @default.
- W1761921570 hasConceptScore W1761921570C207001950 @default.
- W1761921570 hasConceptScore W1761921570C2776366702 @default.
- W1761921570 hasConceptScore W1761921570C2776514930 @default.
- W1761921570 hasConceptScore W1761921570C2776809568 @default.
- W1761921570 hasConceptScore W1761921570C2777226302 @default.
- W1761921570 hasConceptScore W1761921570C2777882243 @default.
- W1761921570 hasConceptScore W1761921570C3019368612 @default.
- W1761921570 hasConceptScore W1761921570C62231903 @default.
- W1761921570 hasConceptScore W1761921570C71924100 @default.
- W1761921570 hasConceptScore W1761921570C86803240 @default.
- W1761921570 hasIssue "8" @default.
- W1761921570 hasLocation W17619215701 @default.
- W1761921570 hasLocation W17619215702 @default.
- W1761921570 hasOpenAccess W1761921570 @default.
- W1761921570 hasPrimaryLocation W17619215701 @default.
- W1761921570 hasRelatedWork W1761921570 @default.
- W1761921570 hasRelatedWork W2003058580 @default.
- W1761921570 hasRelatedWork W2003785477 @default.
- W1761921570 hasRelatedWork W2029027719 @default.
- W1761921570 hasRelatedWork W2246940898 @default.
- W1761921570 hasRelatedWork W2267099497 @default.
- W1761921570 hasRelatedWork W2390041924 @default.
- W1761921570 hasRelatedWork W2400238107 @default.
- W1761921570 hasRelatedWork W2417094998 @default.
- W1761921570 hasRelatedWork W71916131 @default.
- W1761921570 hasVolume "115" @default.
- W1761921570 isParatext "false" @default.
- W1761921570 isRetracted "false" @default.
- W1761921570 magId "1761921570" @default.
- W1761921570 workType "article" @default.